Resultado de investigación por año
Resultado de la investigación 2003 2019
- 1 - 50 de 56 resultados
- Año de publicación, título (descendiente)
Circulating Endothelial Cells From Septic Shock Patients Convert to Fibroblasts Are Associated With the Resuscitation Fluid Dose and Are Biomarkers for Survival Prediction
Tapia, P., Gatica, S., Cortés-Rivera, C., Otero, C., Becerra, A., Riedel, C. A., Cabello-Verrugio, C., Kalergis, A. M. & Simon, F., 1 jul 2019, En : Critical Care Medicine. 47, 7, p. 942-950 9 p.Resultado de la investigación: Article
Endothelial Cells Exhibit Two Waves of P-selectin Surface Aggregation Under Endotoxic and Oxidative Conditions
Barrionuevo, N., Gatica, S., Olivares, P., Cabello-Verrugio, C. & Simon, F., 1 dic 2019, En : Protein Journal. 38, 6, p. 667-674 8 p.Resultado de la investigación: Article
Endotoxemia-induced endothelial fibrosis inhibition improves hypotension, tachycardia, multiple organ dysfunction syndrome, cytokine response, oxidative stress, and survival
Vallejos, A., Olivares, P., Gatica, S., Villegas, V., Echeverria, C., Cabello-Verrugio, C. & Simon, F., 1 ene 2019, En : Laboratory Investigation.Resultado de la investigación: Article
Expression Suppression and Activity Inhibition of TRPM7 Regulate Cytokine Production and Multiple Organ Dysfunction Syndrome During Endotoxemia: a New Target for Sepsis
Gatica, S., Eltit, F., Santibanez, J. F., Varela, D., Cabello-Verrugio, C. & Simon, F., 1 ene 2019, En : Current Molecular Medicine. 19, 8, p. 547-559 13 p.Resultado de la investigación: Article
OxHDL controls LOX-1 expression and plasma membrane localization through a mechanism dependent on NOX/ROS/NF-κB pathway on endothelial cells
Pérez, L., Vallejos, A., Echeverria, C., Varela, D., Cabello-Verrugio, C. & Simon, F., 1 ene 2019, (Accepted/In press) En : Laboratory Investigation.Resultado de la investigación: Article
The p75NTR neurotrophin receptor is required to organize the mature neuromuscular synapse by regulating synaptic vesicle availability
Pérez, V., Bermedo-Garcia, F., Zelada, D., Court, F. A., Pérez, M. Á., Fuenzalida, M., Ábrigo, J., Cabello-Verrugio, C., Moya-Alvarado, G., Tapia, J. C., Valenzuela, V., Hetz, C., Bronfman, F. C. & Henríquez, J. P., 12 sep 2019, En : Acta neuropathologica communications. 7, 1, 1 p.Resultado de la investigación: Article
TRPM7 mediates kidney injury, endothelial hyperpermeability and mortality during endotoxemia
Gatica, S., Villegas, V., Vallejos, A., Olivares, P., Aballai, V., Lagos-Meza, F., Echeverria, C., Cabello-Verrugio, C., Varela, D. & Simon, F., 1 ene 2019, En : Laboratory Investigation.Resultado de la investigación: Article
Central Role of Transforming Growth Factor Type Beta 1 in Skeletal Muscle Dysfunctions: An Update on Therapeutic Strategies
Abrigo, J., Simon, F., Cabrera, D., Cordova, G., Trollet, C. & Cabello-Verrugio, C., 1 ene 2018, En : Current protein & peptide science. 19, 12, p. 1189-1200 12 p.Resultado de la investigación: Article
Gestational hypothyroxinemia affects its offspring with a reduced suppressive capacity impairing the outcome of the experimental autoimmune encephalomyelitis
Haensgen, H., Albornoz, E., Opazo, M. C., Bugueño, K., Jara Fernández, E. L., Binzberger, R., Rivero-Castillo, T., Venegas Salas, L. F., Simon, F., Cabello-Verrugio, C., Elorza, A. A., Kalergis, A. M., Bueno, S. M. & Riedel, C. A., 6 jun 2018, En : Frontiers in Immunology. 9, JUN, 1257.Resultado de la investigación: Article
Preventive Leptin Administration Protects Against Sepsis Through Improving Hypotension, Tachycardia, Oxidative Stress Burst, Multiple Organ Dysfunction, and Increasing Survival
Vallejos, A., Olivares, P., Varela, D., Echeverria, C., Cabello-Verrugio, C., Perez-Leighton, C. & Simon, F., 12 dic 2018, En : Frontiers in Physiology. 9Resultado de la investigación: Article
Sarcopenia in a mice model of chronic liver disease: role of the ubiquitin–proteasome system and oxidative stress
Campos, F., Abrigo, J., Aguirre, F., Garcés, B., Arrese, M., Karpen, S., Cabrera, D., Andía, M. E., Simon, F. & Cabello-Verrugio, C., 20 jun 2018, (Accepted/In press) En : Pflugers Archiv European Journal of Physiology. p. 1-17 17 p.Resultado de la investigación: Article
Somatotropic axis dysfunction in non-alcoholic fatty liver disease: Beneficial hepatic and systemic effects of hormone supplementation
Cabrera, D., Cabello-Verrugio, C., Solís, N., Martín, D. S., Cofré, C., Pizarro, M., Arab, J. P., Abrigo, J., Campos, F., Irigoyen, B., Carrasco-Avino, G., Bezares, K., Riquelme, V., Riquelme, A., Arrese, M. & Barrera, F., 2 may 2018, En : International Journal of Molecular Sciences. 19, 5, 1339.Resultado de la investigación: Article
TGF-β and Hepatocellular Carcinoma: When A Friend Becomes An Enemy
Arrese, M., Hernandez, A., Astete, L., Estrada, L., Cabello-Verrugio, C. & Cabrera, D., 1 ene 2018, En : Current protein & peptide science. 19, 12, p. 1172-1179 8 p.Resultado de la investigación: Article
TGF-β requires the activation of canonical and non-canonical signalling pathways to induce skeletal muscle atrophy
Ábrigo, J., Campos, F., Simon, F., Riedel, C., Cabrera, D., Vilos, C. & Cabello-Verrugio, C., 23 feb 2018, En : Biological Chemistry. 399, 3, p. 253-264 12 p.Resultado de la investigación: Article
Transforming Growth Factor-Beta Family: Advances in Vascular Function and Signaling
Gatica, S., Cabello-Verrugio, C. & Simon, F., 1 ene 2018, En : Current protein & peptide science. 19, 12, p. 1164-1171 8 p.Resultado de la investigación: Article
Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis
Cabrera, D., Wree, A., Povero, D., Solís, N., Hernandez, A., Pizarro, M., Moshage, H., Torres, J., Feldstein, A. E., Cabello-Verrugio, C., Brandan, E., Barrera, F., Arab, J. P. & Arrese, M., 1 dic 2017, En : Scientific Reports. 7, 1, 3491.Resultado de la investigación: Article
Endothelial fibrosis induced by suppressed STAT3 expression mediated by signaling involving the TGF-β1/ALK5/Smad pathway
Becerra, A., Rojas, M., Vallejos, A., Villegas, V., Pérez, L., Cabello-Verrugio, C. & Simon, F., 1 sep 2017, En : Laboratory Investigation. 97, 9, p. 1033-1046 14 p.Resultado de la investigación: Article
The complex of PAMAM-OH dendrimer with angiotensin (1–7) prevented the disuse-induced skeletal muscle atrophy in mice
Márquez-Miranda, V., Abrigo, J., Rivera, J. C., Araya-Durán, I., Aravena, J., Simon, F., Pacheco, N., González-Nilo, F. D. & Cabello-Verrugio, C., 13 mar 2017, En : International Journal of Nanomedicine. 12, p. 1985-1999 15 p.Resultado de la investigación: Article
Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas
Morales, M. G., Abrigo, J., Acuna, M. J., Santos, R. A., Bader, M., Brandan, E., Simon, F., Olguin, H., Cabrera, D. & Cabello-Verrugio, C., 1 abr 2016, En : DMM Disease Models and Mechanisms. 9, 4, p. 441-449 9 p.Resultado de la investigación: Article
Angiotensin-(1-7) Prevents Skeletal Muscle Atrophy Induced by Transforming Growth Factor Type Beta (TGF-β) via Mas Receptor Activation
Ábrigo, J., Simon, F., Cabrera, D. & Cabello-Verrugio, C., 1 nov 2016, En : Cellular Physiology and Biochemistry. 40, 1-2, p. 27-38 12 p.Resultado de la investigación: Article
Diet-Induced Nonalcoholic Fatty Liver Disease Is Associated with Sarcopenia and Decreased Serum Insulin-Like Growth Factor-1
Cabrera, D., Ruiz, A., Cabello-Verrugio, C., Brandan, E., Estrada, L., Pizarro, M., Solis, N., Torres, J., Barrera, F. & Arrese, M., 1 nov 2016, En : Digestive Diseases and Sciences. 61, 11, p. 3190-3198 9 p.Resultado de la investigación: Article
High Fat Diet-Induced Skeletal Muscle Wasting Is Decreased by Mesenchymal Stem Cells Administration: Implications on Oxidative Stress, Ubiquitin Proteasome Pathway Activation, and Myonuclear Apoptosis
Abrigo, J., Rivera, J. C., Aravena, J., Cabrera, D., Simon, F., Ezquer, F., Ezquer, M. & Cabello-Verrugio, C., 1 ene 2016, En : Oxidative Medicine and Cellular Longevity. 2016, 9047821.Resultado de la investigación: Article
Transforming growth factor type beta (TGF-β) requires reactive oxygen species to induce skeletal muscle atrophy
Abrigo, J., Rivera, J. C., Simon, F., Cabrera, D. & Cabello-Verrugio, C., 1 may 2016, En : Cellular Signalling. 28, 5, p. 366-376 11 p.Resultado de la investigación: Article
Angiotensin-(1-7) decreases skeletal muscle atrophy induced by angiotensin II through a Mas receptor-dependent mechanism
Cisternas, F., Morales, M. G., Meneses, C., Simon, F., Brandan, E., Abrigo, J., Vazquez, Y. & Cabello-Verrugio, C., 2015, En : Clinical Science. 128, 5, p. 307-319 13 p.Resultado de la investigación: Article
Apocynin inhibits the upregulation of TGF-β1 expression and ROS production induced by TGF-β in skeletal muscle cells
Abrigo, J., Morales, M. G., Simon, F., Cabrera, D., Capua, G. D. & Cabello-Verrugio, C., 27 jul 2015, En : Phytomedicine. 22, 10, p. 885-893 9 p., 51860.Resultado de la investigación: Article
Endotoxin-induced skeletal muscle wasting is prevented by angiotensin-(1-7) through a p38 MAPK-dependent mechanism
Morales, M. G., Olguín, H., Capua, G. D., Brandan, E., Simon, F. & Cabello-Verrugio, C., 1 ene 2015, En : Clinical Science. 129, 6, p. 461-476 16 p.Resultado de la investigación: Article
Increases in reactive oxygen species enhance vascular endothelial cell migration through a mechanism dependent on the transient receptor potential melastatin 4 ion channel
Sarmiento, D., Montorfano, I., Cerda, O., Cáceres, M., Becerra, A., Cabello-Verrugio, C., Elorza, A. A., Riedel, C., Tapia, P., Velásquez, L. A., Varela, D. & Simon, F., 1 mar 2015, En : Microvascular Research. 98, p. 187-196 10 p.Resultado de la investigación: Article
Renin-angiotensin system: An old player with novel functions in skeletal muscle
Cabello-Verrugio, C., Morales, M. G., Rivera, J. C., Cabrera, D. & Simon, F., 1 may 2015, En : Medicinal Research Reviews. 35, 3, p. 437-463 27 p.Resultado de la investigación: Article
Suppression of transient receptor potential melastatin 4 expression promotes conversion of endothelial cells into fibroblasts via transforming growth factor/activin receptor-like kinase 5 pathway
Echeverría, C., Montorfano, I., Cabello-Verrugio, C., Armisén, R., Varela, D. & Simon, F., 1 ene 2015, En : Journal of Hypertension. 33, 5, p. 981-992 12 p.Resultado de la investigación: Article
The angiotensin-(1–7)/Mas axis reduces myonuclear apoptosis during recovery from angiotensin II-induced skeletal muscle atrophy in mice
Meneses, C., Morales, M. G., Abrigo, J., Simon, F., Brandan, E. & Cabello-Verrugio, C., 1 sep 2015, En : Pflugers Archiv European Journal of Physiology. 467, 9, p. 1975-1984 10 p., A001.Resultado de la investigación: Article
Transforming growth factor type-β inhibits Mas receptor expression in fibroblasts but not in myoblasts or differentiated myotubes; Relevance to fibrosis associated to muscular dystrophies
Cofre, C., Acuña, M. J., Contreras, O., Morales, M. G., Riquelme, C., Cabello-Verrugio, C. & Brandan, E., 1 mar 2015, En : BioFactors. 41, 2, p. 111-120 10 p.Resultado de la investigación: Article
Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis
Cabrera, D., Gutiérrez, J., Cabello-Verrugio, C., Morales, M. G., Mezzano, S., Fadic, R., Casar, J. C., Hancke, J. L. & Brandan, E., 21 mar 2014, En : Skeletal Muscle. 4, 1, 6.Resultado de la investigación: Article
Endotoxin-induced endothelial fibrosis is dependent on expression of transforming growth factors β1 and β2
Echeverría, C., Montorfano, I., Tapia, P., Riedel, C., Cabello-Verrugio, C. & Simon, F., 2014, En : Infection and Immunity. 82, 9, p. 3678-3686 9 p.Resultado de la investigación: Article
Endotoxin-induced vascular endothelial cell migration is dependent on TLR4/NF-κB pathway, NAD(P)H oxidase activation, and transient receptor potential melastatin 7 calcium channel activity
Sarmiento, D., Montorfano, I., Cáceres, M., Echeverría, C., Fernández, R., Cabello-Verrugio, C., Cerda, O., Tapia, P. & Simon, F., 1 ene 2014, En : International Journal of Biochemistry and Cell Biology. 55, p. 11-23 13 p.Resultado de la investigación: Article
Endotoxin induces fibrosis in vascular endothelial cells through a mechanism dependent on transient receptor protein melastatin 7 activity
Echeverría, C., Montorfano, I., Hermosilla, T., Armisén, R., Velásquez, L. A., Cabello-Verrugio, C., Varela, D. & Simon, F., 7 abr 2014, En : PLoS ONE. 9, 4, e94146.Resultado de la investigación: Article
Expression of the Mas receptor is upregulated in skeletal muscle wasting
Morales, M. G., Abrigo, J., Meneses, C., Cisternas, F., Simon, F. & Cabello-Verrugio, C., 1 ene 2014, En : Histochemistry and Cell Biology. 143, 2, p. 131-141 11 p.Resultado de la investigación: Article
Oxidative stress mediates the conversion of endothelial cells into myofibroblasts via a TGF-b1 and TGF-b2-dependent pathway
Montorfano, I., Becerra, A., Cerro, R., Echeverría, C., Sáez, E., Morales, M. G., Fernández, R., Cabello-Verrugio, C. & Simon, F., 1 ene 2014, En : Laboratory Investigation. 94, 10, p. 1068-1082 15 p.Resultado de la investigación: Article
Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-β signalling
Acuña, M. J., Pessina, P., Olguin, H., Cabrera, D., Vio, C. P., Bader, M., Muñoz-canoves, P., Santos, R. A., Cabello-verrugio, C. & Brandan, E., 1 mar 2014, En : Human Molecular Genetics. 23, 5, p. 1237-1249 13 p., ddt514.Resultado de la investigación: Article
The ang-(1-7)/mas-1 axis attenuates the expression and signalling of TGF-β1 induced by angii in mouse skeletal muscle
Morales, M. G., Ábrigo, J., Meneses, C., Simon, F., Cisternas, F., Rivera, J. C., Vazquez, Y. & Cabello-Verrugio, C., 2014, En : Clinical Science. 127, 4, p. 251-264 14 p.Resultado de la investigación: Article
Inhibition of the angiotensin-converting enzyme decreases skeletal muscle fibrosis in dystrophic mice by a diminution in the expression and activity of connective tissue growth factor (CTGF/CCN-2)
Morales, M. G., Cabrera, D., Céspedes, C., Vio, C. P., Vazquez, Y., Brandan, E. & Cabello-Verrugio, C., 1 jul 2013, En : Cell and Tissue Research. 353, 1, p. 173-187 15 p.Resultado de la investigación: Article
Lipopolysaccharide induces a fibrotic-like phenotype in endothelial cells
Echeverría, C., Montorfano, I., Sarmiento, D., Becerra, A., Nuñez-Villena, F., Figueroa, X. F., Cabello-Verrugio, C., Elorza, A. A., Riedel, C. & Simon, F., jun 2013, En : Journal of Cellular and Molecular Medicine. 17, 6, p. 800-814 15 p.Resultado de la investigación: Article
Reducing CTGF/CCN2 slows down mdx muscle dystrophy and improves cell therapy
Morales, M. G., Gutierrez, J., Cabello-Verrugio, C., Cabrera, D., Lipson, K. E., Goldschmeding, R. & Brandan, E., 1 dic 2013, En : Human Molecular Genetics. 22, 24, p. 4938-4951 14 p., ddt352.Resultado de la investigación: Article
Transforming growth factor type beta 1 increases the expression of angiotensin II receptor type 2 by a SMAD- and p38 MAPK-dependent mechanism in skeletal muscle
Painemal, P., Acuña, M. J., Riquelme, C., Brandan, E. & Cabello-Verrugio, C., jul 2013, En : BioFactors. 39, 4, p. 467-475 9 p.Resultado de la investigación: Article
Angiotensin II-induced pro-fibrotic effects require p38MAPK activity and transforming growth factor beta 1 expression in skeletal muscle cells
Morales, M. G., Vazquez, Y., Acuña, M. J., Rivera, J. C., Simon, F., Salas, J. D., Álvarez Ruf, J., Brandan, E. & Cabello-Verrugio, C., 1 nov 2012, En : International Journal of Biochemistry and Cell Biology. 44, 11, p. 1993-2002 10 p.Resultado de la investigación: Article
Angiotensin II receptor type 1 blockade decreases CTGF/CCN2-mediated damage and fibrosis in normal and dystrophic skeletal muscles
Cabello-Verrugio, C., Morales, M. G., Cabrera, D., Vio, C. P. & Brandan, E., 2012, En : Journal of Cellular and Molecular Medicine. 16, 4, p. 752-764 13 p.Resultado de la investigación: Article
The internal region leucine-rich repeat 6 of decorin interacts with low density lipoprotein receptor-related protein-1, modulates Transforming Growth Factor (TGF)-β-dependent signaling, and inhibits TGF-β-dependent fibrotic response in skeletal muscles
Cabello-Verrugio, C., Santander, C., Cofré, C., Acuña, M. J., Melo, F. & Brandan, E., 24 feb 2012, En : Journal of Biological Chemistry. 287, 9, p. 6773-6787 15 p.Resultado de la investigación: Article
Connective tissue growth factor induction by lysophosphatidic acid requires transactivation of transforming growth factor type β receptors and the JNK pathway
Cabello-Verrugio, C., Córdova, G., Vial, C., Zúñiga, L. M. & Brandan, E., 1 feb 2011, En : Cellular Signalling. 23, 2, p. 449-457 9 p.Resultado de la investigación: Article
CTGF/CCN-2 over-expression can directly induce features of skeletal muscle dystrophy
Morales, M. G., Cabello-Verrugio, C., Santander, C., Cabrera, D., Goldschmeding, R. & Brandan, E., dic 2011, En : Journal of Pathology. 225, 4, p. 490-501 12 p.Resultado de la investigación: Article
Fibrotic response induced by angiotensin-II requires NAD(P)H oxidase-induced reactive oxygen species (ROS) in skeletal muscle cells
Cabello-Verrugio, C., Acuña, M. J., Morales, M. G., Becerra, A., Simon, F. & Brandan, E., 8 jul 2011, En : Biochemical and Biophysical Research Communications. 410, 3, p. 665-670 6 p.Resultado de la investigación: Article
TGF-β receptors, in a Smad-independent manner, are required for terminal skeletal muscle differentiation
Droguett, R., Cabello-Verrugio, C., Santander, C. & Brandan, E., 1 ene 2010, En : Experimental Cell Research. 316, 15, p. 2487-2503 17 p.Resultado de la investigación: Article