CLAUDIO ALEJANDRO CABELLO VERRUGIO

PhD

    • 1581 Citas
    • 25 Índice H
    20032019
    Los cambios que haya realizado en Pure se mostrarán aquí próximamente.

    Resultado de la investigación 2003 2019

    2019
    Septic Shock
    Resuscitation
    Endothelial Cells
    Fibroblasts
    Biomarkers

    Endothelial dysfunction in pregnancy metabolic disorders

    Echeverria, C., Eltit, F., Santibanez, J. F., Gatica, S., Cabello-Verrugio, C. & Simon, F., 1 ene 2019, En : Biochimica et Biophysica Acta - Molecular Basis of Disease.

    Resultado de la investigación: Review article

    Pregnancy
    Gestational Diabetes
    Vascular Endothelium
    Hyperlipidemias
    Endothelium
    Endotoxemia
    Multiple Organ Failure
    Tachycardia
    Hypotension
    Oxidative Stress

    OxHDL controls LOX-1 expression and plasma membrane localization through a mechanism dependent on NOX/ROS/NF-κB pathway on endothelial cells

    Pérez, L., Vallejos, A., Echeverria, C., Varela, D., Cabello-Verrugio, C. & Simon, F., 1 ene 2019, (Accepted/In press) En : Laboratory Investigation.

    Resultado de la investigación: Article

    HDL Lipoproteins
    Endothelial Cells
    Cell Membrane
    Class E Scavenger Receptors
    Respiratory Burst
    2018
    3 Citas (Scopus)

    Central Role of Transforming Growth Factor Type Beta 1 in Skeletal Muscle Dysfunctions: An Update on Therapeutic Strategies

    Abrigo, J., Simon, F., Cabrera, D., Cordova, G., Trollet, C. & Cabello-Verrugio, C., 1 ene 2018, En : Current protein & peptide science. 19, 12, p. 1189-1200 12 p.

    Resultado de la investigación: Article

    Transforming Growth Factors
    Transforming Growth Factor beta
    Muscle
    Skeletal Muscle
    Atrophy
    7 Citas (Scopus)

    Combined therapies for Duchenne muscular dystrophy to optimize treatment efficacy

    Cordova, G., Negroni, E., Cabello-Verrugio, C., Mouly, V. & Trollet, C., 10 abr 2018, En : Frontiers in Genetics. 9, APR, 114.

    Resultado de la investigación: Short survey

    Duchenne Muscular Dystrophy
    Muscular Dystrophies
    Therapeutics
    Cell- and Tissue-Based Therapy
    Muscles

    Gestational hypothyroxinemia affects its offspring with a reduced suppressive capacity impairing the outcome of the experimental autoimmune encephalomyelitis

    Haensgen, H., Albornoz, E., Opazo, M. C., Bugueño, K., Jara Fernández, E. L., Binzberger, R., Rivero-Castillo, T., Venegas Salas, L. F., Simon, F., Cabello-Verrugio, C., Elorza, A. A., Kalergis, A. M., Bueno, S. M. & Riedel, C. A., 6 jun 2018, En : Frontiers in Immunology. 9, JUN, 1257.

    Resultado de la investigación: Article

    Autoimmune Experimental Encephalomyelitis
    T-Lymphocytes
    Spleen
    Interleukin-10
    Eragrostis
    1 Cita (Scopus)

    Oxidative Stress in Disease and Aging: Mechanisms and Therapies 2018

    Cabello-Verrugio, C., Vilos, C., Rodrigues-Diez, R. & Estrada, L., 1 ene 2018, En : Oxidative Medicine and Cellular Longevity. 2018, 1 p.

    Resultado de la investigación: Editorial

    9 Citas (Scopus)

    Role of Oxidative Stress as Key Regulator of Muscle Wasting during Cachexia

    Ábrigo, J., Elorza, A. A., Riedel, C. A., Vilos, C., Simon, F., Cabrera, D., Estrada, L. & Cabello-Verrugio, C., 1 ene 2018, En : Oxidative Medicine and Cellular Longevity. 2018, 1 p.

    Resultado de la investigación: Review article

    Sarcopenia in a mice model of chronic liver disease: role of the ubiquitin–proteasome system and oxidative stress

    Campos, F., Abrigo, J., Aguirre, F., Garcés, B., Arrese, M., Karpen, S., Cabrera, D., Andía, M. E., Simon, F. & Cabello-Verrugio, C., 20 jun 2018, (Accepted/In press) En : Pflugers Archiv European Journal of Physiology. p. 1-17 17 p.

    Resultado de la investigación: Article

    Sarcopenia
    Oxidative stress
    Liver
    Muscle
    Liver Diseases
    2 Citas (Scopus)

    Somatotropic axis dysfunction in non-alcoholic fatty liver disease: Beneficial hepatic and systemic effects of hormone supplementation

    Cabrera, D., Cabello-Verrugio, C., Solís, N., Martín, D. S., Cofré, C., Pizarro, M., Arab, J. P., Abrigo, J., Campos, F., Irigoyen, B., Carrasco-Avino, G., Bezares, K., Riquelme, V., Riquelme, A., Arrese, M. & Barrera, F., 2 may 2018, En : International Journal of Molecular Sciences. 19, 5, 1339.

    Resultado de la investigación: Article

    diets
    hormones
    Hormones
    High Fat Diet
    Nutrition
    1 Cita (Scopus)

    TGF-β and Hepatocellular Carcinoma: When A Friend Becomes An Enemy

    Arrese, M., Hernandez, A., Astete, L., Estrada, L., Cabello-Verrugio, C. & Cabrera, D., 1 ene 2018, En : Current protein & peptide science. 19, 12, p. 1172-1179 8 p.

    Resultado de la investigación: Article

    Transforming Growth Factor beta
    Hepatocellular Carcinoma
    Fibrosis
    Cell growth
    Neoplasms
    5 Citas (Scopus)

    TGF-β requires the activation of canonical and non-canonical signalling pathways to induce skeletal muscle atrophy

    Ábrigo, J., Campos, F., Simon, F., Riedel, C., Cabrera, D., Vilos, C. & Cabello-Verrugio, C., 23 feb 2018, En : Biological Chemistry. 399, 3, p. 253-264 12 p.

    Resultado de la investigación: Article

    Muscular Atrophy
    Transforming Growth Factor beta
    Muscle
    Skeletal Muscle
    Chemical activation
    2 Citas (Scopus)

    Transforming Growth Factor-Beta Family: Advances in Vascular Function and Signaling

    Gatica, S., Cabello-Verrugio, C. & Simon, F., 1 ene 2018, En : Current protein & peptide science. 19, 12, p. 1164-1171 8 p.

    Resultado de la investigación: Article

    Transforming Growth Factor beta
    Blood Vessels
    Publications
    Health
    2017
    11 Citas (Scopus)

    Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis

    Cabrera, D., Wree, A., Povero, D., Solís, N., Hernandez, A., Pizarro, M., Moshage, H., Torres, J., Feldstein, A. E., Cabello-Verrugio, C., Brandan, E., Barrera, F., Arab, J. P. & Arrese, M., 1 dic 2017, En : Scientific Reports. 7, 1, 3491.

    Resultado de la investigación: Article

    Inflammasomes
    Fatty Liver
    Inflammation
    Liver
    Hep G2 Cells
    7 Citas (Scopus)

    Endothelial fibrosis induced by suppressed STAT3 expression mediated by signaling involving the TGF-β1/ALK5/Smad pathway

    Becerra, A., Rojas, M., Vallejos, A., Villegas, V., Pérez, L., Cabello-Verrugio, C. & Simon, F., 1 sep 2017, En : Laboratory Investigation. 97, 9, p. 1033-1046 14 p.

    Resultado de la investigación: Article

    STAT3 Transcription Factor
    Transforming Growth Factors
    Fibrosis
    Endothelial Cells
    Extracellular Matrix Proteins
    28 Citas (Scopus)

    Endothelial-to-mesenchymal transition: Cytokine-mediated pathways that determine endothelial fibrosis under inflammatory conditions

    Pérez, L., Muñoz-Durango, N., Riedel, C. A., Echeverría, C., Kalergis, A. M., Cabello-Verrugio, C. & Simon, F., 1 feb 2017, En : Cytokine and Growth Factor Reviews. 33, p. 41-54 14 p.

    Resultado de la investigación: Short survey

    Pathology
    Fibrosis
    Cytokines
    Inflammation
    Oxidative stress
    5 Citas (Scopus)

    Oxidative Stress in Disease and Aging: Mechanisms and Therapies 2016

    Cabello-Verrugio, C., Simon, F., Trollet, C. & Santibañez, J. F., 1 ene 2017, En : Oxidative Medicine and Cellular Longevity. 2017, 4310469.

    Resultado de la investigación: Editorial

    4 Citas (Scopus)

    Skeletal muscle wasting: New role of nonclassical renin-angiotensin system

    Cabello-Verrugio, C., Rivera, J. C. & Garcia, D., 1 may 2017, En : Current Opinion in Clinical Nutrition and Metabolic Care. 20, 3, p. 158-163 6 p.

    Resultado de la investigación: Review article

    Renin-Angiotensin System
    Skeletal Muscle
    Fibrosis
    Therapeutic Human Experimentation
    Proto-Oncogene Proteins c-akt
    5 Citas (Scopus)

    The complex of PAMAM-OH dendrimer with angiotensin (1–7) prevented the disuse-induced skeletal muscle atrophy in mice

    Márquez-Miranda, V., Abrigo, J., Rivera, J. C., Araya-Durán, I., Aravena, J., Simon, F., Pacheco, N., González-Nilo, F. D. & Cabello-Verrugio, C., 13 mar 2017, En : International Journal of Nanomedicine. 12, p. 1985-1999 15 p.

    Resultado de la investigación: Article

    Dendrimers
    Muscular Atrophy
    Angiotensins
    Muscle
    Skeletal Muscle
    2016
    21 Citas (Scopus)

    Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas

    Morales, M. G., Abrigo, J., Acuna, M. J., Santos, R. A., Bader, M., Brandan, E., Simon, F., Olguin, H., Cabrera, D. & Cabello-Verrugio, C., 1 abr 2016, En : DMM Disease Models and Mechanisms. 9, 4, p. 441-449 9 p.

    Resultado de la investigación: Article

    Muscular Atrophy
    Muscle
    Skeletal Muscle
    Immobilization
    Renin-Angiotensin System
    6 Citas (Scopus)
    Muscular Atrophy
    Transforming Growth Factor beta
    Skeletal Muscle
    Myosin Heavy Chains
    7-Ala-angiotensin (1-7)
    17 Citas (Scopus)

    Diet-Induced Nonalcoholic Fatty Liver Disease Is Associated with Sarcopenia and Decreased Serum Insulin-Like Growth Factor-1

    Cabrera, D., Ruiz, A., Cabello-Verrugio, C., Brandan, E., Estrada, L., Pizarro, M., Solis, N., Torres, J., Barrera, F. & Arrese, M., 1 nov 2016, En : Digestive Diseases and Sciences. 61, 11, p. 3190-3198 9 p.

    Resultado de la investigación: Article

    Sarcopenia
    Somatomedins
    Diet
    Muscles
    Liver
    14 Citas (Scopus)
    Oxidative stress
    High Fat Diet
    Proteasome Endopeptidase Complex
    Nutrition
    Ubiquitin
    10 Citas (Scopus)

    Oxidative stress in disease and aging: Mechanisms and therapies

    Cabello-Verrugio, C., Ruiz-Ortega, M., Mosqueira, M. & Simon, F., 2016, En : Oxidative Medicine and Cellular Longevity. 2016, 8786564.

    Resultado de la investigación: Editorial

    19 Citas (Scopus)

    Transforming growth factor type beta (TGF-β) requires reactive oxygen species to induce skeletal muscle atrophy

    Abrigo, J., Rivera, J. C., Simon, F., Cabrera, D. & Cabello-Verrugio, C., 1 may 2016, En : Cellular Signalling. 28, 5, p. 366-376 11 p.

    Resultado de la investigación: Article

    Muscular Atrophy
    Transforming Growth Factor beta
    Reactive Oxygen Species
    Skeletal Muscle
    Skeletal Muscle Fibers
    2015
    31 Citas (Scopus)

    Angiotensin-(1-7) decreases skeletal muscle atrophy induced by angiotensin II through a Mas receptor-dependent mechanism

    Cisternas, F., Morales, M. G., Meneses, C., Simon, F., Brandan, E., Abrigo, J., Vazquez, Y. & Cabello-Verrugio, C., 2015, En : Clinical Science. 128, 5, p. 307-319 13 p.

    Resultado de la investigación: Article

    Muscular Atrophy
    Angiotensin II
    Skeletal Muscle
    Myosin Heavy Chains
    Skeletal Muscle Fibers
    11 Citas (Scopus)

    Apocynin inhibits the upregulation of TGF-β1 expression and ROS production induced by TGF-β in skeletal muscle cells

    Abrigo, J., Morales, M. G., Simon, F., Cabrera, D., Capua, G. D. & Cabello-Verrugio, C., 27 jul 2015, En : Phytomedicine. 22, 10, p. 885-893 9 p., 51860.

    Resultado de la investigación: Article

    Transforming Growth Factor beta
    Muscle Cells
    Reactive Oxygen Species
    Skeletal Muscle
    Up-Regulation
    22 Citas (Scopus)

    Endotoxin-induced skeletal muscle wasting is prevented by angiotensin-(1-7) through a p38 MAPK-dependent mechanism

    Morales, M. G., Olguín, H., Capua, G. D., Brandan, E., Simon, F. & Cabello-Verrugio, C., 1 ene 2015, En : Clinical Science. 129, 6, p. 461-476 16 p.

    Resultado de la investigación: Article

    p38 Mitogen-Activated Protein Kinases
    Endotoxins
    Skeletal Muscle
    Lipopolysaccharides
    Muscular Atrophy
    19 Citas (Scopus)

    Increases in reactive oxygen species enhance vascular endothelial cell migration through a mechanism dependent on the transient receptor potential melastatin 4 ion channel

    Sarmiento, D., Montorfano, I., Cerda, O., Cáceres, M., Becerra, A., Cabello-Verrugio, C., Elorza, A. A., Riedel, C., Tapia, P., Velásquez, L. A., Varela, D. & Simon, F., 1 mar 2015, En : Microvascular Research. 98, p. 187-196 10 p.

    Resultado de la investigación: Article

    Endothelial cells
    Oxidative stress
    Ion Channels
    Cell Movement
    Reactive Oxygen Species
    28 Citas (Scopus)

    Renin-angiotensin system: An old player with novel functions in skeletal muscle

    Cabello-Verrugio, C., Morales, M. G., Rivera, J. C., Cabrera, D. & Simon, F., 1 may 2015, En : Medicinal Research Reviews. 35, 3, p. 437-463 27 p.

    Resultado de la investigación: Article

    Renin-Angiotensin System
    Skeletal Muscle
    Insulin Resistance
    Fibrosis
    Atrophy
    12 Citas (Scopus)
    Growth Factor Receptors
    Transforming Growth Factors
    Transforming Growth Factor beta
    Fibrosis
    Endothelial Cells
    26 Citas (Scopus)

    The angiotensin-(1–7)/Mas axis reduces myonuclear apoptosis during recovery from angiotensin II-induced skeletal muscle atrophy in mice

    Meneses, C., Morales, M. G., Abrigo, J., Simon, F., Brandan, E. & Cabello-Verrugio, C., 1 sep 2015, En : Pflugers Archiv European Journal of Physiology. 467, 9, p. 1975-1984 10 p., A001.

    Resultado de la investigación: Article

    Muscular Atrophy
    Angiotensins
    Angiotensin II
    Muscle
    Skeletal Muscle
    5 Citas (Scopus)

    Transforming growth factor type-β inhibits Mas receptor expression in fibroblasts but not in myoblasts or differentiated myotubes; Relevance to fibrosis associated to muscular dystrophies

    Cofre, C., Acuña, M. J., Contreras, O., Morales, M. G., Riquelme, C., Cabello-Verrugio, C. & Brandan, E., 1 mar 2015, En : BioFactors. 41, 2, p. 111-120 10 p.

    Resultado de la investigación: Article

    Muscular Dystrophies
    Myoblasts
    Skeletal Muscle Fibers
    Transforming Growth Factors
    Fibroblasts
    2014
    18 Citas (Scopus)

    Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis

    Cabrera, D., Gutiérrez, J., Cabello-Verrugio, C., Morales, M. G., Mezzano, S., Fadic, R., Casar, J. C., Hancke, J. L. & Brandan, E., 21 mar 2014, En : Skeletal Muscle. 4, 1, 6.

    Resultado de la investigación: Article

    Inbred mdx Mouse
    Cell- and Tissue-Based Therapy
    Skeletal Muscle
    Fibrosis
    Duchenne Muscular Dystrophy
    19 Citas (Scopus)

    Endotoxin-induced endothelial fibrosis is dependent on expression of transforming growth factors β1 and β2

    Echeverría, C., Montorfano, I., Tapia, P., Riedel, C., Cabello-Verrugio, C. & Simon, F., 2014, En : Infection and Immunity. 82, 9, p. 3678-3686 9 p.

    Resultado de la investigación: Article

    Transforming Growth Factors
    Endotoxins
    Fibrosis
    Endothelial Cells
    Smad3 Protein
    16 Citas (Scopus)
    NADPH Oxidase
    Endothelial cells
    Calcium Channels
    Endotoxins
    Cell Movement
    21 Citas (Scopus)

    Endotoxin induces fibrosis in vascular endothelial cells through a mechanism dependent on transient receptor protein melastatin 7 activity

    Echeverría, C., Montorfano, I., Hermosilla, T., Armisén, R., Velásquez, L. A., Cabello-Verrugio, C., Varela, D. & Simon, F., 7 abr 2014, En : PLoS ONE. 9, 4, e94146.

    Resultado de la investigación: Article

    Endothelial cells
    endotoxins
    fibrosis
    blood vessels
    Endotoxins
    17 Citas (Scopus)

    Expression of the Mas receptor is upregulated in skeletal muscle wasting

    Morales, M. G., Abrigo, J., Meneses, C., Cisternas, F., Simon, F. & Cabello-Verrugio, C., 1 ene 2014, En : Histochemistry and Cell Biology. 143, 2, p. 131-141 11 p.

    Resultado de la investigación: Article

    Angiotensin II
    Skeletal Muscle
    Lipopolysaccharides
    Immobilization
    Muscular Atrophy
    49 Citas (Scopus)

    Oxidative stress mediates the conversion of endothelial cells into myofibroblasts via a TGF-b1 and TGF-b2-dependent pathway

    Montorfano, I., Becerra, A., Cerro, R., Echeverría, C., Sáez, E., Morales, M. G., Fernández, R., Cabello-Verrugio, C. & Simon, F., 1 ene 2014, En : Laboratory Investigation. 94, 10, p. 1068-1082 15 p.

    Resultado de la investigación: Article

    Myofibroblasts
    Oxidative Stress
    Endothelial Cells
    Inflammation
    p38 Mitogen-Activated Protein Kinases
    77 Citas (Scopus)

    Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-β signalling

    Acuña, M. J., Pessina, P., Olguin, H., Cabrera, D., Vio, C. P., Bader, M., Muñoz-canoves, P., Santos, R. A., Cabello-verrugio, C. & Brandan, E., 1 mar 2014, En : Human Molecular Genetics. 23, 5, p. 1237-1249 13 p., ddt514.

    Resultado de la investigación: Article

    Muscle Strength
    Transforming Growth Factors
    Inbred mdx Mouse
    Duchenne Muscular Dystrophy
    Muscles
    30 Citas (Scopus)

    The ang-(1-7)/mas-1 axis attenuates the expression and signalling of TGF-β1 induced by angii in mouse skeletal muscle

    Morales, M. G., Ábrigo, J., Meneses, C., Simon, F., Cisternas, F., Rivera, J. C., Vazquez, Y. & Cabello-Verrugio, C., 2014, En : Clinical Science. 127, 4, p. 251-264 14 p.

    Resultado de la investigación: Article

    Transforming Growth Factors
    Angiotensin II
    Skeletal Muscle
    p38 Mitogen-Activated Protein Kinases
    Phosphorylation
    2013
    42 Citas (Scopus)

    Inhibition of the angiotensin-converting enzyme decreases skeletal muscle fibrosis in dystrophic mice by a diminution in the expression and activity of connective tissue growth factor (CTGF/CCN-2)

    Morales, M. G., Cabrera, D., Céspedes, C., Vio, C. P., Vazquez, Y., Brandan, E. & Cabello-Verrugio, C., 1 jul 2013, En : Cell and Tissue Research. 353, 1, p. 173-187 15 p.

    Resultado de la investigación: Article

    Connective Tissue Growth Factor
    Inbred mdx Mouse
    Peptidyl-Dipeptidase A
    Skeletal Muscle
    Fibrosis
    32 Citas (Scopus)

    Lipopolysaccharide induces a fibrotic-like phenotype in endothelial cells

    Echeverría, C., Montorfano, I., Sarmiento, D., Becerra, A., Nuñez-Villena, F., Figueroa, X. F., Cabello-Verrugio, C., Elorza, A. A., Riedel, C. & Simon, F., jun 2013, En : Journal of Cellular and Molecular Medicine. 17, 6, p. 800-814 15 p.

    Resultado de la investigación: Article

    Lipopolysaccharides
    Endothelial Cells
    Phenotype
    Fibrosis
    Systemic Inflammatory Response Syndrome
    31 Citas (Scopus)

    Oxidative stress-modulated TRPM ion channels in cell dysfunction and pathological conditions in humans

    Simon, F., Varela, D. & Cabello-Verrugio, C., 1 ene 2013, En : Cellular Signalling. 25, 7, p. 1614-1624 11 p.

    Resultado de la investigación: Review article

    Ion Channels
    Oxidative Stress
    Transient Receptor Potential Channels
    Oxidation-Reduction
    Channelopathies
    62 Citas (Scopus)

    Reducing CTGF/CCN2 slows down mdx muscle dystrophy and improves cell therapy

    Morales, M. G., Gutierrez, J., Cabello-Verrugio, C., Cabrera, D., Lipson, K. E., Goldschmeding, R. & Brandan, E., 1 dic 2013, En : Human Molecular Genetics. 22, 24, p. 4938-4951 14 p., ddt352.

    Resultado de la investigación: Article

    Inbred mdx Mouse
    Cell- and Tissue-Based Therapy
    Duchenne Muscular Dystrophy
    Muscles
    Dystrophin