• 542 Citas
  • 13 Índice H
20072019
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Perfil personal

Research interests

We are currently working on:

  • Infection Biology: Which aims to understand the infectious diseases both at a cellular and molecular level so as to be able to control them and prevent them better in the future, with a main focus on bacterial infectious diseases.
  • Genomic Epidemiology under the «One Health» concept: Which aims to understand the factors that drive the emergence and transmission of infectious diseases. In addition to the emergence of Antimicrobial Resistance in our country, through alliances with hospitals, clinics and national governmental entities.
  • The third axis seeks to integrate the previous two in order to generate impact in Biomedicine, through the development of diagnostic tools (through the integration of data from genomic epidemiology and antimicrobial resistance) as with therapeutic potential (through modification and reutilization of bacterial weapons with therapeutic objectives).

Red Colaboración externa reciente a nivel de país. Sumergirse en la información haciendo clic en los puntos.

Resultado de la investigación 2007 2019

  • 542 Citas
  • 13 Índice H
  • 19 Article
  • 2 Comment/debate
  • 1 Letter

A FACS-Based Genome-wide CRISPR Screen Reveals a Requirement for COPI in Chlamydia trachomatis Invasion

Park, J. S., Helble, J. D., Lazarus, J. E., Yang, G., Blondel, C. J., Doench, J. G., Starnbach, M. N. & Waldor, M. K., 25 ene 2019, En : iScience. 11, p. 71-84 14 p.

Resultado de la investigación: Article

Acceso abierto
Clustered Regularly Interspaced Short Palindromic Repeats
Chlamydia trachomatis
Heparitin Sulfate
Flow Cytometry
Genome

Antimicrobial resistance in E. coli isolated from dairy calves and bedding material

Astorga, F., Navarrete-Talloni, M. J., Miró, M. P., Bravo, V., Toro, M., Blondel, C. J. & Hervé-Claude, L. P., nov 2019, En : Heliyon. 5, 11, e02773.

Resultado de la investigación: Article

Acceso abierto
dairy calves
animal breeding
animal science
microbiology
antibiotic resistance

Transposon-insertion sequencing screens unveil requirements for EHEC growth and intestinal colonization

Warr, A. R., Hubbard, T. P., Munera, D., Blondel, C. J., Zur Wiesch, P. A., Abel, S., Wang, X., Davis, B. M. & Waldor, M. K., 1 ene 2019, En : PLoS Pathogens. 15, 8, e1007652.

Resultado de la investigación: Article

Acceso abierto
Enterohemorrhagic Escherichia coli
Escherichia coli O157
Growth
Colon
Rabbits
8 Citas (Scopus)

CRISPR screen reveals that EHEC’s T3SS and Shiga Toxin rely on shared host factors for infection

Pacheco, A. R., Lazarus, J. E., Sit, B., Schmieder, S., Lencer, W. I., Blondel, C. J., Doench, J. G., Davis, B. M. & Waldor, M. K., 1 may 2018, En : mBio. 9, 3, e01003-18.

Resultado de la investigación: Article

Acceso abierto
Clustered Regularly Interspaced Short Palindromic Repeats
Shiga Toxin
Enterohemorrhagic Escherichia coli
Sphingolipids
Escherichia coli Infections
6 Citas (Scopus)

Exploring the genomic traits of non-toxigenic Vibrio parahaemolyticus strains isolated in southern Chile

Castillo, D., Pérez-Reytor, D., Plaza, N., Ramírez-Araya, S., Blondel, C. J., Corsini, G., Bastías, R., Loyola, D. E., Jaña, V., Pavez, L. & García, K., 8 feb 2018, En : Frontiers in Microbiology. 9, FEB, 161.

Resultado de la investigación: Article

Acceso abierto
Vibrio parahaemolyticus
Chile
Genome
Pandemics
Multigene Family