• 218 Citas
  • 8 Índice H
20032019
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Resultado de la investigación 2003 2019

  • 218 Citas
  • 8 Índice H
  • 13 Article
Filtro
Article
2019

Anthraquinone Derivative Reduces Tau Oligomer Progression by Inhibiting Cysteine-Cysteine Interaction

Areche, C., Zapata, F., González, M., Díaz, E., Montecinos, R., Hernández, M., Melo, F. & Cornejo, A., 1 ene 2019, En : ChemistryOpen.

Resultado de la investigación: Article

Acceso abierto
Anthraquinones
Oligomers
Cysteine
tau Proteins
Fluorescence
2018
Depsides
Umbilicaria
tau Proteins
Lichens
Molecular modeling
8 Citas (Scopus)

Secondary metabolite profiling of species of the genus usnea by UHPLC-ESI-OT-MS-MS

Salgado, F., Albornoz, L., Cortéz, C., Stashenko, E., Urrea-Vallejo, K., Nagles, E., Galicia-Virviescas, C., Cornejo, A., Ardiles, A., Simirgiotis, M., García-Beltrán, O. & Areche, C., 1 ene 2018, En : Molecules. 23, 1, 54.

Resultado de la investigación: Article

Usnea
lichens
Lichens
metabolites
Metabolites
2017
10 Citas (Scopus)

Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to β sheet in tau protein linked to Alzheimer’s disease

Cornejo, A., Aguilar Sandoval, F., Caballero, L., Machuca, L., Muñoz, P., Caballero, J., Perry, G., Ardiles, A., Areche, C. & Melo, F., 1 ene 2017, En : Journal of Enzyme Inhibition and Medicinal Chemistry. 32, 1, p. 945-953 9 p.

Resultado de la investigación: Article

tau Proteins
Alzheimer Disease
Tauopathies
Diterpenes
Atomic Force Microscopy
10 Citas (Scopus)

The Polyphenol Altenusin Inhibits in Vitro Fibrillization of Tau and Reduces Induced Tau Pathology in Primary Neurons

Chua, S. W., Cornejo, A., Van Eersel, J., Stevens, C. H., Vaca, I., Cueto, M., Kassiou, M., Gladbach, A., Macmillan, A., Lewis, L., Whan, R. & Ittner, L. M., 19 abr 2017, En : ACS Chemical Neuroscience. 8, 4, p. 743-751 9 p.

Resultado de la investigación: Article

Polyphenols
Pathology
Neurons
Neurofibrillary Tangles
Agglomeration
2016
15 Citas (Scopus)

Secondary metabolites in ramalina terebrata detected by UHPLC/ESI/MS/MS and identification of parietin as tau protein inhibitor

Cornejo, A., Salgado, F., Caballero, J., Vargas, R., Simirgiotis, M. & Areche, C., 18 ago 2016, En : International Journal of Molecular Sciences. 17, 8, 1303.

Resultado de la investigación: Article

tau Proteins
metabolites
Metabolites
inhibitors
Mass Spectrometry
2015
7 Citas (Scopus)

Seco-taondiol, an unusual meroterpenoid from the Chilean seaweed Stypopodium flabelliforme and its gastroprotective effect in mouse model

Areche, C., Benites, J., Cornejo, A., Ruiz, L. M., García-Beltrán, O., Simirgiotis, M. J. & Sepúlveda, B., 1 abr 2015, En : Marine Drugs. 13, 4, p. 1726-1738 13 p.

Resultado de la investigación: Article

Seaweed
Ethylmaleimide
Indomethacin
Prostaglandins
Molecular Structure
2012
3 Citas (Scopus)

A novel monoclonal antibody against the c-terminus of β-tubulin recognizes endocytic organelles in trypanosoma cruzi

Cornejo, A., De Oliveira, C. R., Würtele, M., Chung, J., Hilpert, K. & Schenkman, S., 1 ene 2012, En : Protein and Peptide Letters. 19, 6, p. 636-643 8 p.

Resultado de la investigación: Article

Trypanosoma cruzi
Tubulin
Organelles
Monoclonal Antibodies
Microtubules
2011
32 Citas (Scopus)

Fulvic acid inhibits aggregation and promotes disassembly of tau fibrils associated with alzheimer's disease

Cornejo, A., Jiménez, J. M., Caballero, L., Melo, F. & MacCioni, R. B., 2011, En : Journal of Alzheimer's Disease. 27, 1, p. 143-153 11 p.

Resultado de la investigación: Article

Alzheimer Disease
tau Proteins
Humic Substances
Amyloid Plaques
Drug Delivery Systems
31 Citas (Scopus)

Mechanisms of tau self-aggregation and neurotoxicity

Farías, G., Cornejo, A., Jiménez, J., Guzmán, L. & Maccioni, R. B., 1 sep 2011, En : Current Alzheimer Research. 8, 6, p. 608-614 7 p.

Resultado de la investigación: Article

Tauopathies
Alzheimer Disease
tau Proteins
Neurofibrillary Tangles
Post Translational Protein Processing
2009
46 Citas (Scopus)

Trypanosome prereplication machinery contains a single functional Orc1/Cdc6 protein, which is typical of archaea

De Melo Godoy, P. D., Nogueira-Junior, L. A., Paes, L. S., Cornejo, A., Martins, R. M., Silber, A. M., Schenkman, S. & Elias, M. C., oct 2009, En : Eukaryotic Cell. 8, 10, p. 1592-1603 12 p.

Resultado de la investigación: Article

Trypanosomiasis
Archaea
Trypanosoma brucei brucei
Replication Origin
Proteins
2008
25 Citas (Scopus)

Calcineurin B of the human protozoan parasite Trypanosoma cruzi is involved in cell invasion

Araya, J. E., Cornejo, A., Orrego, P. R., Cordero, E. M., Cortéz, M., Olivares, H., Neira, I., Sagua, H., Franco da Silveira, J., Yoshida, N. & González, J., 1 jul 2008, En : Microbes and Infection. 10, 8, p. 892-900 9 p.

Resultado de la investigación: Article

Calcineurin
Trypanosoma cruzi
Parasites
HeLa Cells
Cyclosporine
2003
31 Citas (Scopus)

A novel protein phosphatase 2A (PP2A) is involved in the transformation of human protozoan parasite Trypanosoma cruzi

González, J., Cornejo, A., Santos, M. R. M., Cordero, E. M., Gutiérrez, B., Porcile, P., Mortara, R. A., Sagua, H., Da Silveira, J. F. & Araya, J. E., 15 sep 2003, En : Biochemical Journal. 374, 3, p. 647-656 10 p.

Resultado de la investigación: Article

Protein Phosphatase 2
Trypanosoma cruzi
Parasites
Okadaic Acid
Genes