Ventilación de alta frecuencia oscilatoria en pacientes pediátricos

Translated title of the contribution: High-frequency oscillatory ventilation in pediatric patients

Alejandro Donoso F., Pablo Cruces R., José León B., Milena Ramírez A., Jorge Camacho A.

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)


Introduction: High-frequency oscillatory ventilation (HFOV) uses small tidal volumes, often smaller than the anatomic dead space, with high respiratory rates (> 1 Hz). This therapeutic option has become more popular in our country in the last years. Study objectives: To review the clinical experience with HFOV in our Pediatric Intensive Care Unit and to describe the patient's characteristics, HFOV strategies and outcome. Patients: A prospective study included patients less than 16 years old with Acute Respiratory Distress Syndrome (ARDS) refractary to conventional mechanical ventilation (CMV). We compare two periods (1999-2001 and 2002-2004). Measurements and results: Forty-nine patients underwent onto 51 episodes of HFO ventilation, 80% presented with primary ARDS. Previous conventional ventilation was 47 hours long. The median value of the oxygenation index (OI) at the beginning of HFOV was 24. Mean airway pressure was initially set at 9 cmH 2O above the value in conventional ventilation. All the patients presented a decrease of their OI and ventilation was improved during the first 48 hours of therapy. Median duration on HFOV was 102 hours. The most frequent side effect was transient hypotension (25%). In the second period we observed a decrease in hemodynamic complications and also an increase in HFO duration. The mortality rate was 33% (22% due to pulmonary cause). Conclusion: HFOV is an effective therapy for pediatric respiratory failure refractory to conventional mechanical ventilation.

Translated title of the contributionHigh-frequency oscillatory ventilation in pediatric patients
Original languageSpanish
Pages (from-to)21-30
Number of pages10
JournalRevista Chilena de Enfermedades Respiratorias
Issue number1
Publication statusPublished - Mar 2006

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


Dive into the research topics of 'High-frequency oscillatory ventilation in pediatric patients'. Together they form a unique fingerprint.

Cite this