The impact of the micronutrient iodine in health and diseases

Ma Cecilia Opazo, Irenice Coronado-Arrázola, Omar P. Vallejos, Rodrigo Moreno-Reyes, Carlos Fardella, Lorena Mosso, Alexis M. Kalergis, Susan M. Bueno, Claudia A. Riedel

Research output: Contribution to journalReview articlepeer-review

21 Citations (Scopus)


Adequate iodine nutrition is crucial for all mammals by playing his starring role as a component of thyroid hormones, which are key regulators of cellular processes for life such as differentiation, growth, function, and metabolism. Deficiency or excess of iodine in the diet are worldwide highly frequent conditions that are responsible of health problems like hypothyroidism, hypothyroxinemia, goiter, thyroiditis, hyperthyroidism, and autoimmune thyroid diseases among others. The incorporation of iodine in salt or other nutrients resolved the consequences of severe iodine deficiency like goiter, cretinism. However, this strategy in several countries led to other ailments like Hashimoto autoimmune thyroiditis, hyperthyroidism, and hypothyroidism. The goal of this review is to analyze and discuss the different aspects of iodine nutrition for human health comprising its biological role through thyroid hormones, pathogen control, and the regulation of the intestinal microbiota.

Original languageEnglish
JournalCritical Reviews in Food Science and Nutrition
Publication statusAccepted/In press - 2020


  • Bactericide
  • intestinal microbiota
  • iodine
  • nutrition
  • thyroid diseases
  • thyroid hormones

ASJC Scopus subject areas

  • Food Science
  • Industrial and Manufacturing Engineering


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