The four subunits of mitochondrial respiratory complex II are encoded by multiple nuclear genes and targeted to mitochondria in Arabidopsis thaliana

Pablo Figueroa, Gabriel Léon, Alvaro Elorza, Loreto Holuigue, Alejandro Araya, Xavier Jordana

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

Mitochondrial respiratory complex II contains four subunits: a flavoprotein (SDH1), an iron-sulphur subunit (SDH2) and two membrane anchor subunits (SDH3 and SDH4). We have found that in Arabidopsis thaliana SDH1 and SDH3 are encoded by two, and SDH4 by one nuclear genes, respectively. All these encoded polypeptides are found to be imported into isolated plant mitochondria. While both SDH1 proteins are highly conserved when compared to their counterparts in other organisms, SDH3 and SDH4 share little similarity with non-plant homologues. Expression of SDH1-1, SDH3 and SDH4 genes was detected in all tissues analysed, with the highest steady-state mRNA levels found in flowers and inflorescences. In contrast, the second SDH1 gene (SDH1-2) is expressed at a low level.

Original languageEnglish
Pages (from-to)725-734
Number of pages10
JournalPlant Molecular Biology
Volume50
Issue number4-5
DOIs
Publication statusPublished - 2002

Keywords

  • Flavoprotein
  • Membrane anchor
  • Mitochondrial targeting
  • Plant mitochondria
  • Succinate dehydrogenase

ASJC Scopus subject areas

  • Agronomy and Crop Science
  • Genetics
  • Plant Science

Fingerprint

Dive into the research topics of 'The four subunits of mitochondrial respiratory complex II are encoded by multiple nuclear genes and targeted to mitochondria in Arabidopsis thaliana'. Together they form a unique fingerprint.

Cite this