The A12 acetylcholinesterase and polypeptide composition of electric organ basal lamina of electrophorus and some torpedinae fishes

Nibaldo C. Inestrosa, Bernardita Méndez

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Basal lamina (BL) of Torpedo, Discopyge and Electrophorus electric organs was purified in order to establish polypeptide composition and association with acetylcholinesterase (AChE). Results indicate that BL presents a distinct peptide pattern and that the A12 form of AChE is directly attached to it. Comparison of the species studied demonstrated similarities both in polypeptide composition and AChE content of the purified BL. Extractions of BL with solutions of high ionic strength, guanidine–HCl and acetic acid indicated the differential solubilization of various domains of BL polypeptides.

Original languageEnglish
Pages (from-to)41-48
Number of pages8
JournalCell Biochemistry and Function
Volume1
Issue number1
DOIs
Publication statusPublished - 1983

Keywords

  • AChR clusters
  • basal lamina peptides
  • cholinergic synapse
  • electric organ
  • extracellular matrix
  • Polypeptides
  • synaptic AChE A form

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Cell Biology
  • Medicine(all)

Fingerprint

Dive into the research topics of 'The A<sub>12</sub> acetylcholinesterase and polypeptide composition of electric organ basal lamina of electrophorus and some torpedinae fishes'. Together they form a unique fingerprint.

Cite this