The 24,000 dalton subunit and the activity of yeast RNA polymerases

Pablo Valenzuela, Graeme I. Bell, William J. Rutter

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

The subunits of RNA polymerase I are partially resolved during density gradient centrifugation. An analysis of the relative subunit composition with respect to specific catalytic activity shows that the molar ratio of the 24,000 dalton subunit directly correlates with polymerase activity. Since this polypeptide is found also in polymerases II and III, it may be required for activity of all yeast nuclear RNA polymerases.

Original languageEnglish
Pages (from-to)26-31
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume71
Issue number1
DOIs
Publication statusPublished - 12 Jul 1976

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

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