The subunits of RNA polymerase I are partially resolved during density gradient centrifugation. An analysis of the relative subunit composition with respect to specific catalytic activity shows that the molar ratio of the 24,000 dalton subunit directly correlates with polymerase activity. Since this polypeptide is found also in polymerases II and III, it may be required for activity of all yeast nuclear RNA polymerases.
|Number of pages||6|
|Journal||Biochemical and Biophysical Research Communications|
|Publication status||Published - 12 Jul 1976|
ASJC Scopus subject areas
- Molecular Biology