Spread of NDM-5 and OXA-181 carbapenemase-producing Escherichia coli in Chad

Oumar Ouchar Mahamat, Manon Lounnas, Mallorie Hide, Abelsalam Tidjani, Julio Benavides, Abibatou Diack, Calèbe Somasse, Kadidja Gamougam, Christian Carrière, Dominique Decré, Anne Laure Bañuls, Hélène Jean-Pierre, Yann Dumont, Fabrice Compain, Sylvain Godreuil

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

We detected for the first time blaNDM-5 and blaOXA-181 in Escherichia coli isolates from hospitalized patients and healthy volunteers in Chad. These resistance genes were located on IncX3 and IncF plasmids. Despite the large diversity of E. coli clones, the identified resistant intestinal isolates belonged mainly to the same sequence type.

Original languageEnglish
Article numbere00646-19
JournalAntimicrobial Agents and Chemotherapy
Volume63
Issue number11
DOIs
Publication statusPublished - Nov 2019

Keywords

  • Carbapenemases
  • Chad
  • Clinical samples
  • Escherichia coli
  • Fecal carriage prevalence

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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