Serum osteocalcin in normal menstrual cycle.

J. M. López Moreno, G. González, C. Campino, A. M. Salvatierra, H. B. Croxatto

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Serum osteocalcin (OC) was serially measured along an ovulatory menstrual cycle in 4 healthy unmedicated volunteers (age 33-38 years). During the study the women maintained their normal diet and daily physical activity. Starting at days 4-5 of the cycle, blood samples were taken between 09-11 AM every 2 or 3 days for OC, FSH, LH, E2 and P determinations. Daily ultrasound assessment of ovulation was performed in all subjects between days 7-18 of the cycle. Hormone determinations and OC were performed by RIA. While blood levels of FSH, LH, E2 and P changed during the cycle, according to the expected ovulatory pattern, serum OC concentrations remained stable during the cycle in each subject. In conclusion, serum OC is independent of the gonadotropin and ovarian steroid variations during the normal menstrual cycle.

Original languageEnglish
Pages (from-to)37-40
Number of pages4
Issue number1
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Medicine(all)


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