Role of copper in prion diseases: Deleterious or beneficial?

Keyphrases

• PrPC 100%
• Prion Disease 100%
• PrPSc 36%
• Neurodegenerative Diseases 9%
• Beneficial Effects 9%
• Expression Level 9%
• Physiological Function 9%
• Cellular Prion Protein 9%
• GPI-anchored Protein (GPI-AP) 9%
• Intracellular Trafficking 9%
• Copper Effect 9%
• Endocytosis 9%
• Endocytic 9%
• Ligand-binding Domain 9%
• Copper Transport 9%
• Microdomain 9%
• Pathogenic Mechanism 9%
• Disease Therapy 9%
• Detrimental Effects 9%
• Surface Proteins 9%
• Copper Metabolism 9%
• Lipid Rafts 9%
• Copper Binding 9%
• Prion Pathogenesis 9%
• Misfolding 9%
• Conformational Distortion 9%
• Far Left 9%
• Contradictory Observations 9%
• Prion 9%
• Prion Conversion 9%
• Conformational Conversion 9%

Biochemistry, Genetics and Molecular Biology

• Transmissible Spongiform Encephalopathy 100%
• Prion 50%
• Conformation 33%
• Isoform 16%
• Metabolic Pathway 16%
• Prion 16%
• Binding Domain 16%
• Endocytosis 16%
• Cell Surface Protein 16%
• Lipid Raft 16%
• Intracellular Trafficking 16%

Neuroscience

• Transmissible Spongiform Encephalopathy 100%
• Prion 50%
• Neurodegenerative Disorder 16%
• Metabolic Pathway 16%
• Behavior (Neuroscience) 16%
• Prion Protein 16%
• Endocytosis 16%
• Lipid Raft 16%
• Cell Surface Protein 16%
• Intracellular Trafficking 16%