Prevalence and Clinical Consideration of Anatomical Variants of the Splenic Artery: A Systematic Review and Meta-Analysis

Juan José Valenzuela-Fuenzalida, Daniela Martínez-Hernández, Daniela Pérez-Jiménez, Pablo Nova Baeza, Álvaro Becerra-Farfan, Mathias Orellana-Donoso, Alejandro Bruna Mejias, Qareen Hania Syed, Macarena Rodriguez Luengo, Joe Iwanaga

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

Background: The spleen is the largest secondary immune organ in the body. Knowledge regarding the normal splenic vascular anatomy and its anatomical variants is crucial in the medical practice of surgeons and radiologists and is useful for diagnostic evaluations and the guidance of various surgical procedures. Hence, in this research, we aim to characterize the behavior of the lineal or splenic artery in humans from an anatomoclinical point of view. Methods: A systematic search was carried out in electronic databases to compile the available literature on the research subject. Searches were undertaken in the following databases: Medline, Scielo, Wos, Cinahl, Scopus, and Google Scholar. The search terms were “Splenic artery”, “Splenic vascularization”, “Anatomical variations’’, “Splenic organ”, and “Clinical anatomy”. Results: From the 35 studies included in this review, clinical correlations of anatomical variations in the splenic artery with surgical procedures in the abdominal region were reported in 8 studies. These correlations are mainly associated with surgical procedures for the pancreas, liver, stomach, and bile ducts through imaging of the spleen. To verify our conclusions, the risk of bias of the anatomical studies was measured using the AQUA checklist. Conclusions: Recognition of the usual anatomy and anatomical variants of the splenic artery is crucial for both morphology professionals and clinicians addressing the abdominal region and its vascular components. In this review, we determined that the splenic artery could present a variation in its origin or entry into the splenic hilum, which could mean that in any abdominal intervention there may be complications if the splenic artery variation is overlooked. More anatomic clinical studies considering this variation in both diagnostic and surgical processes are suggested for further investigations.

Original languageEnglish
Article number3510
JournalApplied Sciences (Switzerland)
Volume13
Issue number6
DOIs
Publication statusPublished - Mar 2023

Keywords

  • anatomical variations
  • clinical anatomy
  • spleen
  • spleen vascularization
  • splenic artery

ASJC Scopus subject areas

  • Materials Science(all)
  • Instrumentation
  • Engineering(all)
  • Process Chemistry and Technology
  • Computer Science Applications
  • Fluid Flow and Transfer Processes

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