Potential involvement of post-translational modifications as a mechanism modulating selective proteolysis after fertilization

Maria Imschenetzky, Marcia Puchi, Violeta Morin, Fredy Diaz, M. Isabel Oliver, Martin Montecino

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

The role of proteolysis during fertilization has been investigated only to a very limited extent as compared with its role on the control of cell cycle progression. In this report, we discuss briefly the proteases involved in fertilization, their relevance in the egg-sperm interaction and in the chromatin remodeling that occurs before the reestablishment of the diploid condition of the zygote. We further emphasize how the post-translational modifications of target proteins modulate these proteolytic events.

Original languageEnglish
Pages (from-to)149-157
Number of pages9
JournalJournal of Cellular Biochemistry
Volume76
Issue numberSUPPL. 32/33
Publication statusPublished - 1999

Keywords

  • Fertilization/proteolysis
  • Phosphorylation
  • Poly(ADP- ribosylation)
  • Ubiquitination

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology

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