Pesquisa de infección tuberculosa latente en personal de la salud en cuatro instituciones de salud en Santiago de Chile

Translated title of the contribution: Latent tuberculosis infection screening in healthcare workers in four large hospitals in Santiago, Chile

Mariluz Hernández, Carlos Casar, Patricia García, Verónica Morales, Nora Mamani, Natalia Gómez-Cofré, Patricia Pizarro, M. Elvira Balcells

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Background: It is currently unknown which is the prevalence of latent tuberculosis infection in healthcare workers in Chile, but this group has been described as at higher risk of developing active tuberculosis than general population. Objectives: To determine the prevalence of latent tuberculosis infection in a sample of healthcare workers from at risk areas. Methodology: A cross-sectional, descriptive study, conducted in health care workers from clinical laboratories or respiratory care areas in four hospitals in Santiago. Latent tuberculosis infection detection was determined by Quantiferon® TB Gold In Tube testing (QFT). Results: QFT resulted positive in 20 of 76 (26.3%) of the individuals tested. Test positivity reached 62.5% among the personnel that reported history of past TB contact in the community, 50% among the personnel who belonged to the national tuberculosis control program and 38% among those doing induced sputum, acid fast smear or mycobacterial cultures. The proportion of individuals with positive QFT was significantly lower in those personnel who had no such risk factors (15.7%, p = 0.03). The proportion of latent tuberculosis infection also increased in direct relation to the age of the subject. Conclusion: Latent tuberculosis infection as detected by QFT testing was highly prevalent in healthcare workers included in the present study. Further exploring the limitations and possible scenarios for this new diagnostic tool is needed, with emphasis on health personnel at higher-risk and younger individuals.

Translated title of the contributionLatent tuberculosis infection screening in healthcare workers in four large hospitals in Santiago, Chile
Original languageSpanish
Pages (from-to)254-260
Number of pages7
JournalRevista Chilena de Infectologia
Volume31
Issue number3
DOIs
Publication statusPublished - 1 Jan 2014

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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