Parvovirus-derived endogenous viral elements in two South American rodent genomes

Gloria Arriagada; Robert J. Gifford

doi:10.1128/JVI.01173-14

Parvovirus-derived endogenous viral elements in two South American rodent genomes

Gloria Arriagada, Robert J. Gifford

Life Sciences School

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

We describe endogenous viral elements (EVEs) derived from parvoviruses (family Parvoviridae) in the genomes of the longtailed chinchilla (Chinchilla lanigera) and the degu (Octodon degus). The novel EVEs include dependovirus-related elements and representatives of a clearly distinct parvovirus lineage that also has endogenous representatives in marsupial genomes. In the degu, one dependovirus-derived EVE was found to carry an intact reading frame and was differentially expressed in vivo, with increased expression in the liver.

Original language	English
Pages (from-to)	12158-12162
Number of pages	5
Journal	Journal of Virology
Volume	88
Issue number	20
DOIs	https://doi.org/10.1128/JVI.01173-14
Publication status	Published - 2014

ASJC Scopus subject areas

Microbiology
Immunology
Insect Science
Virology

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abstract = "We describe endogenous viral elements (EVEs) derived from parvoviruses (family Parvoviridae) in the genomes of the longtailed chinchilla (Chinchilla lanigera) and the degu (Octodon degus). The novel EVEs include dependovirus-related elements and representatives of a clearly distinct parvovirus lineage that also has endogenous representatives in marsupial genomes. In the degu, one dependovirus-derived EVE was found to carry an intact reading frame and was differentially expressed in vivo, with increased expression in the liver.",

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AB - We describe endogenous viral elements (EVEs) derived from parvoviruses (family Parvoviridae) in the genomes of the longtailed chinchilla (Chinchilla lanigera) and the degu (Octodon degus). The novel EVEs include dependovirus-related elements and representatives of a clearly distinct parvovirus lineage that also has endogenous representatives in marsupial genomes. In the degu, one dependovirus-derived EVE was found to carry an intact reading frame and was differentially expressed in vivo, with increased expression in the liver.

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Parvovirus-derived endogenous viral elements in two South American rodent genomes

Abstract

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