TY - JOUR
T1 - Nuevos enfoques moleculares
T2 - En la regulación de la adipogénesis. El papel de la conexina 43
AU - Rojas-Gomez, Diana Marcela
AU - Davila, Lisse Angarita
AU - Cohen-Massabo, Maria Alejandra
AU - Giacometto, Marcela
AU - Rojas, Joselyn
AU - Wilches-Duran, Sandra
AU - Graterol-Rivas, Modesto
AU - Cerda, Marco
AU - Contreras-Velasquez, Julio
AU - Graterol-Silva, Rosemily
AU - Torres, Maritza
AU - Ortiz, Rina
AU - Siguencia, Wilson
AU - Gonzalez-Casanova, Jorge Enrique
PY - 2016
Y1 - 2016
N2 - The global prevalence of obesity has been increased rapidly over the past few years mainly due to changes in the lifestyle of the population with a significant increase in energy consumption and decreased levels of physical activity. As a result, the scientific community is interested in a deeper understanding of the mechanisms that regulate the pathophysiology of obesity. In this context, adipogenesis process is an important target of study to understand the obesity and associated pathologies. Recently has been emerged important evidence that involve gap junction channel protein connexin 43 (C×43) in the regulation of processes related to adipogenesis, whose role is fundamentally anti-adipogenic. However, new functions of C×43 in the regulation of adipose tissue function also continued to emerge.
AB - The global prevalence of obesity has been increased rapidly over the past few years mainly due to changes in the lifestyle of the population with a significant increase in energy consumption and decreased levels of physical activity. As a result, the scientific community is interested in a deeper understanding of the mechanisms that regulate the pathophysiology of obesity. In this context, adipogenesis process is an important target of study to understand the obesity and associated pathologies. Recently has been emerged important evidence that involve gap junction channel protein connexin 43 (C×43) in the regulation of processes related to adipogenesis, whose role is fundamentally anti-adipogenic. However, new functions of C×43 in the regulation of adipose tissue function also continued to emerge.
KW - Adipogenesis
KW - Connexin 43
KW - Gap junctions
KW - Obesity
KW - Physical activity
UR - http://www.scopus.com/inward/record.url?scp=85019157890&partnerID=8YFLogxK
M3 - Artículo
AN - SCOPUS:85019157890
SN - 0798-0264
VL - 35
SP - 86
EP - 91
JO - Archivos Venezolanos de Farmacologia y Terapeutica
JF - Archivos Venezolanos de Farmacologia y Terapeutica
IS - 4
ER -
