Non-abortive effect of Adhatoda vasica spissum leaf extract by oral administration in rats

R. Burgos; M. Forcelledo; H. Wagner; A. Müller; J. Hancke; G. Wikman; H. Croxatto

doi:10.1016/S0944-7113(97)80061-X

Non-abortive effect of Adhatoda vasica spissum leaf extract by oral administration in rats

R. Burgos
, M. Forcelledo
, H. Wagner
, A. Müller
, J. Hancke
, G. Wikman
, H. Croxatto

Medicine School

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

The possible abortive effect of an extract of Adhatoda vasica leaf spissum, was studied in rats. The principal alkaloid detected in the extract was vasicine (0.85 ±0.03%). The extract (325 mg/kg/day) was administered with a gastric cannula to a group of 5 pregnant females between day 1 and 9 of pregnancy. In another experiment 9 pregnant females received in the water 0.25 and 2.5% of Adhatoda vasica between day 1 and 9 of pregnancy. It was concluded that the administration of Adhatoda vasica did not produce abortion in any of the treated groups.

Original language	English
Pages (from-to)	145-149
Number of pages	5
Journal	Phytomedicine
Volume	4
Issue number	2
DOIs	https://doi.org/10.1016/S0944-7113(97)80061-X
Publication status	Published - Jun 1997

Keywords

Abortive effect
Adhatoda vasica
Rats
Vasicine

ASJC Scopus subject areas

Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine

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10.1016/S0944-7113(97)80061-X

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title = "Non-abortive effect of Adhatoda vasica spissum leaf extract by oral administration in rats",

abstract = "The possible abortive effect of an extract of Adhatoda vasica leaf spissum, was studied in rats. The principal alkaloid detected in the extract was vasicine (0.85 ±0.03\%). The extract (325 mg/kg/day) was administered with a gastric cannula to a group of 5 pregnant females between day 1 and 9 of pregnancy. In another experiment 9 pregnant females received in the water 0.25 and 2.5\% of Adhatoda vasica between day 1 and 9 of pregnancy. It was concluded that the administration of Adhatoda vasica did not produce abortion in any of the treated groups.",

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year = "1997",

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T1 - Non-abortive effect of Adhatoda vasica spissum leaf extract by oral administration in rats

AU - Burgos, R.

AU - Forcelledo, M.

AU - Wagner, H.

AU - Müller, A.

AU - Hancke, J.

AU - Wikman, G.

AU - Croxatto, H.

PY - 1997/6

Y1 - 1997/6

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AB - The possible abortive effect of an extract of Adhatoda vasica leaf spissum, was studied in rats. The principal alkaloid detected in the extract was vasicine (0.85 ±0.03%). The extract (325 mg/kg/day) was administered with a gastric cannula to a group of 5 pregnant females between day 1 and 9 of pregnancy. In another experiment 9 pregnant females received in the water 0.25 and 2.5% of Adhatoda vasica between day 1 and 9 of pregnancy. It was concluded that the administration of Adhatoda vasica did not produce abortion in any of the treated groups.

KW - Abortive effect

KW - Adhatoda vasica

KW - Rats

KW - Vasicine

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M3 - Article

AN - SCOPUS:0342619941

SN - 0944-7113

VL - 4

SP - 145

EP - 149

JO - Phytomedicine

JF - Phytomedicine

IS - 2

ER -

Non-abortive effect of Adhatoda vasica spissum leaf extract by oral administration in rats

Abstract

Keywords

ASJC Scopus subject areas

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