Non-abortive effect of Adhatoda vasica spissum leaf extract by oral administration in rats

R. Burgos; M. Forcelledo; H. Wagner; A. Müller; J. Hancke; G. Wikman; H. Croxatto

doi:10.1016/S0944-7113(97)80061-X

Non-abortive effect of Adhatoda vasica spissum leaf extract by oral administration in rats

R. Burgos, M. Forcelledo, H. Wagner, A. Müller, J. Hancke, G. Wikman, H. Croxatto

Medicine School

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

The possible abortive effect of an extract of Adhatoda vasica leaf spissum, was studied in rats. The principal alkaloid detected in the extract was vasicine (0.85 ±0.03%). The extract (325 mg/kg/day) was administered with a gastric cannula to a group of 5 pregnant females between day 1 and 9 of pregnancy. In another experiment 9 pregnant females received in the water 0.25 and 2.5% of Adhatoda vasica between day 1 and 9 of pregnancy. It was concluded that the administration of Adhatoda vasica did not produce abortion in any of the treated groups.

Original language	English
Pages (from-to)	145-149
Number of pages	5
Journal	Phytomedicine
Volume	4
Issue number	2
DOIs	https://doi.org/10.1016/S0944-7113(97)80061-X
Publication status	Published - Jun 1997

Keywords

Abortive effect
Adhatoda vasica
Rats
Vasicine

ASJC Scopus subject areas

Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine

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10.1016/S0944-7113(97)80061-X

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abstract = "The possible abortive effect of an extract of Adhatoda vasica leaf spissum, was studied in rats. The principal alkaloid detected in the extract was vasicine (0.85 ±0.03%). The extract (325 mg/kg/day) was administered with a gastric cannula to a group of 5 pregnant females between day 1 and 9 of pregnancy. In another experiment 9 pregnant females received in the water 0.25 and 2.5% of Adhatoda vasica between day 1 and 9 of pregnancy. It was concluded that the administration of Adhatoda vasica did not produce abortion in any of the treated groups.",

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AU - Burgos, R.

AU - Forcelledo, M.

AU - Wagner, H.

AU - Müller, A.

AU - Hancke, J.

AU - Wikman, G.

AU - Croxatto, H.

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Non-abortive effect of Adhatoda vasica spissum leaf extract by oral administration in rats

Abstract

Keywords

ASJC Scopus subject areas

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