New synthesis and characterization of the sodium 3-N-acetylamino-2,4,6-triiodobenzoate. Antibacterial activity evaluation

Victor Kesternich, Pedro García, Rolando Martínez

Research output: Contribution to journalArticlepeer-review

Abstract

A new synthesis and chemical characterization by mass and infrared spectroscopy of sodium 3-N-acetylamine-2,4,6-triiodobenzoate (sodium acetrizoate), a compound used as contrast agent, has been developed. For its preparation, a new method consisting of three stages has been worked out, using 3-aminobenzoic acid as a substrate. Both the intermediate 4 and the product 5 showed antibacterial activity over Pseudomona aeruginosa ATCC and. Shigella flexneri.

Original languageEnglish
Pages (from-to)49-52
Number of pages4
JournalJournal of the Chilean Chemical Society
Volume47
Issue number1
DOIs
Publication statusPublished - Mar 2002

Keywords

  • Bactericidal effect
  • Contrast agent
  • Organoiodine

ASJC Scopus subject areas

  • Chemistry(all)

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