New Insights and Potential Therapeutic Interventions in Metabolic Diseases

Vicente Javier Clemente-Suárez, Alexandra Martín-Rodríguez, Laura Redondo-Flórez, Clara López-Mora, Rodrigo Yáñez-Sepúlveda, José Francisco Tornero-Aguilera

Research output: Contribution to journalReview articlepeer-review

6 Citations (Scopus)

Abstract

Endocrine homeostasis and metabolic diseases have been the subject of extensive research in recent years. The development of new techniques and insights has led to a deeper understanding of the mechanisms underlying these conditions and opened up new avenues for diagnosis and treatment. In this review, we discussed the rise of metabolic diseases, especially in Western countries, the genetical, psychological, and behavioral basis of metabolic diseases, the role of nutrition and physical activity in the development of metabolic diseases, the role of single-cell transcriptomics, gut microbiota, epigenetics, advanced imaging techniques, and cell-based therapies in metabolic diseases. Finally, practical applications derived from this information are made.

Original languageEnglish
Article number10672
JournalInternational Journal of Molecular Sciences
Volume24
Issue number13
DOIs
Publication statusPublished - Jul 2023

Keywords

  • advanced imaging techniques
  • cell-based therapies
  • epigenetics
  • genetic
  • gut
  • microbiota
  • nutrition
  • physical activity
  • psychology
  • single-cell transcriptomics

ASJC Scopus subject areas

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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