Abstract
1. The effects of hemicholinium (HC-3) on several autonomic agents in the isolated rat vas deferens were investigated. 2. HC-3 reduced slightly the effects of NE and DA. 3. The responses by cholinergic agents on the M1-ACh receptors were not modified, however HC-3 reduced, significantly, the responses on the M2-ACh receptors. 4. These results suggest that HC-3 besides its anticholinergic properties possesses ability to interact with adrenoceptors in the isolated rat vas deferens.
Original language | English |
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Pages (from-to) | 643-645 |
Number of pages | 3 |
Journal | General Pharmacology |
Volume | 18 |
Issue number | 6 |
DOIs | |
Publication status | Published - 1987 |
ASJC Scopus subject areas
- Pharmacology