Abstract
Mitochondrial dysfunction is a hallmark of numerous diseases, including neurodegenerative disorders, metabolic disorders, and cancer. Mitochondrial transfer, the transfer of mitochondria from one cell to another, has recently emerged as a potential therapeutic approach for restoring mitochondrial function in diseased cells. In this review, we summarize the current understanding of mitochondrial transfer, including its mechanisms, potential therapeutic applications, and impact on cell death pathways. We also discuss the future directions and challenges in the field of mitochondrial transfer as a novel therapeutic approach in disease diagnosis and treatment.
Original language | English |
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Article number | 8848 |
Journal | International Journal of Molecular Sciences |
Volume | 24 |
Issue number | 10 |
DOIs | |
Publication status | Published - May 2023 |
Keywords
- cancer
- cell death
- disease diagnosis
- disease treatment
- metabolic disorders
- mitochondrial transfer
- neurodegenerative diseases
ASJC Scopus subject areas
- Catalysis
- Molecular Biology
- Spectroscopy
- Computer Science Applications
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry