Mitochondrial Transfer as a Novel Therapeutic Approach in Disease Diagnosis and Treatment

Vicente Javier Clemente-Suárez, Alexandra Martín-Rodríguez, Rodrigo Yáñez-Sepúlveda, José Francisco Tornero-Aguilera

Research output: Contribution to journalReview articlepeer-review

18 Citations (Scopus)


Mitochondrial dysfunction is a hallmark of numerous diseases, including neurodegenerative disorders, metabolic disorders, and cancer. Mitochondrial transfer, the transfer of mitochondria from one cell to another, has recently emerged as a potential therapeutic approach for restoring mitochondrial function in diseased cells. In this review, we summarize the current understanding of mitochondrial transfer, including its mechanisms, potential therapeutic applications, and impact on cell death pathways. We also discuss the future directions and challenges in the field of mitochondrial transfer as a novel therapeutic approach in disease diagnosis and treatment.

Original languageEnglish
Article number8848
JournalInternational Journal of Molecular Sciences
Issue number10
Publication statusPublished - May 2023


  • cancer
  • cell death
  • disease diagnosis
  • disease treatment
  • metabolic disorders
  • mitochondrial transfer
  • neurodegenerative diseases

ASJC Scopus subject areas

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry


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