Isolation of a novel Aggregatibacter actinomycetemcomitans serotype b bacteriophage capable of lysing bacteria within a biofilm

Mario Castillo-Ruiz, Enrique D. Vinés, Camilo Montt, Jorge Fernández, José Manuel Delgado, Juan Carlos Hormazábal, Mauricio Bittner

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

A bacteriophage specific for Aggregatibacter actinomycetemcomitans serotype b, able to kill the bacterium within a biofilm, was isolated. Random mutagenesis of this phage rendered a bacteriophage able to kill 99% of the bacteria within a biofilm. This is the first report of a biocontrol experiment against A. actinomycetemcomitans.

Original languageEnglish
Pages (from-to)3157-3159
Number of pages3
JournalApplied and Environmental Microbiology
Volume77
Issue number9
DOIs
Publication statusPublished - May 2011

ASJC Scopus subject areas

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology
  • Ecology

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