We studied the effect of nonsteroid antiinflammatory (Indomethacin, R), in the palate fusion of rat embryos from different strains with variable susceptibility and also the influence of glucocorticoids. Indomethacin inhibits the fusion of the palate process with variable rate depending of the rat strain. In reciprocal inbred we observed that the effect is greater in embryo from susceptible females than from resistant females. This demonstrates that there are a maternal influence in the induction of cleft palate due to Indomethacin.
|Translated title of the contribution||Maternal influence on susceptibility to cleft palate (1)|
|Number of pages||6|
|Journal||Revista de la Facultad de Odontologia (Santiago, Chile)|
|Publication status||Published - Jan 1990|
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