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Hypoxia increases androgen receptor activity in prostate cancer cells
Soo Yeon Park
, Yun Jeong Kim
, Allen C. Gao
, James L. Mohler
, Sergio A. Onate
, Alejandro A. Hidalgo
, Clement Ip
, Eun Mi Park
, Sun Young Yoon
, Young Mee Park
Medicine School
Research output
:
Contribution to journal
›
Article
›
peer-review
70
Citations (Scopus)
Overview
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Keyphrases
Androgen Deprivation Therapy
9%
Androgen Receptor
100%
Androgen Signaling
100%
Androgens
36%
Chromatin Immunoprecipitation (ChIP)
9%
Confocal Microscopy
9%
DU145
9%
Gene Activity
9%
Hypoxia
100%
Hypoxia Treatment
27%
Hypoxia-reoxygenation
9%
Hypoxic Tumors
9%
Ligand-dependent
9%
LNCaP
9%
Microenvironment
9%
Most Common Form
9%
Normoxic Conditions
9%
Poor Clinical Outcomes
9%
Prostate Cancer
9%
Prostate Cancer Cells
100%
Prostate Radiotherapy
9%
Prostate-specific Antigen
18%
R1881
36%
Receptor Binding
9%
Receptor Function
18%
Receptor Recruitment
9%
Receptor Transactivation
9%
Receptor Translocation
9%
Recurrent Prostate Cancer
9%
Reporter Gene
9%
Responsive Element
27%
Stimulatory Effect
18%
Synthetic Androgen
9%
Tissue Oxygenation
9%
Transient Hypoxia
9%
Treatment Resistance
9%
Tumor
9%
Tumor Environment
9%
Tumor Hypoxia
9%
Medicine and Dentistry
Androgen
42%
Androgen Receptor
100%
Cancer Cell
100%
Cancer Therapy
7%
Chromatin Immunoprecipitation
7%
Confocal Microscopy
7%
Gene Activity
7%
Hypoxia
100%
Metribolone
28%
Neoplasm
14%
Promoter Region
7%
Prostate Cancer
100%
Prostate Specific Antigen
14%
Receptor Binding
7%
Reporter Gene
7%
Sensitization
7%
Transactivation
7%
Tumor Hypoxia
7%
Pharmacology, Toxicology and Pharmaceutical Science
Androgen
42%
Androgen Receptor
100%
Chromatin Immunoprecipitation
7%
Confocal Microscopy
7%
Hypoxia
100%
Metribolone
28%
Neoplasm
21%
Prostate Cancer
100%
Prostate Specific Antigen
14%