Gold nanoparticles for photothermally controlled drug release

Ariel R. Guerrero; Natalia Hassan; Carlos A. Escobar; Fernando Albericio; Marcelo J. Kogan; Eyleen Araya

doi:10.2217/nnm.14.126

Gold nanoparticles for photothermally controlled drug release

Ariel R. Guerrero, Natalia Hassan, Carlos A. Escobar, Fernando Albericio, Marcelo J. Kogan, Eyleen Araya

Exact Sciences School

Research output: Contribution to journal › Review article › peer-review

50 Citations (Scopus)

Abstract

In this article, we describe how nanoparticles work in photothermally triggered drug delivery, starting with a description of the plasmon resonance and the photothermal effect, and how this is used to release a drug. Then, we describe the four major functionalization strategies and each of their different applications. Finally, we discuss the biodistribution and toxicity of these systems and the necessary requirements for the use of gold nanoparticles for spatially and temporally controlling drug release through the photothermal effect.

Original language	English
Pages (from-to)	2023-2039
Number of pages	17
Journal	Nanomedicine
Volume	9
Issue number	13
DOIs	https://doi.org/10.2217/nnm.14.126
Publication status	Published - 1 Sept 2014

Keywords

cancer
drug delivery
near-infrared irradiation
photothermal release
spatial and temporal release

ASJC Scopus subject areas

Bioengineering
Medicine (miscellaneous)
Biomedical Engineering
General Materials Science

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2217/nnm.14.126

Cite this

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title = "Gold nanoparticles for photothermally controlled drug release",

abstract = "In this article, we describe how nanoparticles work in photothermally triggered drug delivery, starting with a description of the plasmon resonance and the photothermal effect, and how this is used to release a drug. Then, we describe the four major functionalization strategies and each of their different applications. Finally, we discuss the biodistribution and toxicity of these systems and the necessary requirements for the use of gold nanoparticles for spatially and temporally controlling drug release through the photothermal effect.",

keywords = "cancer, drug delivery, near-infrared irradiation, photothermal release, spatial and temporal release",

author = "Guerrero, {Ariel R.} and Natalia Hassan and Escobar, {Carlos A.} and Fernando Albericio and Kogan, {Marcelo J.} and Eyleen Araya",

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TY - JOUR

T1 - Gold nanoparticles for photothermally controlled drug release

AU - Guerrero, Ariel R.

AU - Hassan, Natalia

AU - Escobar, Carlos A.

AU - Albericio, Fernando

AU - Kogan, Marcelo J.

AU - Araya, Eyleen

PY - 2014/9/1

Y1 - 2014/9/1

N2 - In this article, we describe how nanoparticles work in photothermally triggered drug delivery, starting with a description of the plasmon resonance and the photothermal effect, and how this is used to release a drug. Then, we describe the four major functionalization strategies and each of their different applications. Finally, we discuss the biodistribution and toxicity of these systems and the necessary requirements for the use of gold nanoparticles for spatially and temporally controlling drug release through the photothermal effect.

AB - In this article, we describe how nanoparticles work in photothermally triggered drug delivery, starting with a description of the plasmon resonance and the photothermal effect, and how this is used to release a drug. Then, we describe the four major functionalization strategies and each of their different applications. Finally, we discuss the biodistribution and toxicity of these systems and the necessary requirements for the use of gold nanoparticles for spatially and temporally controlling drug release through the photothermal effect.

KW - cancer

KW - drug delivery

KW - near-infrared irradiation

KW - photothermal release

KW - spatial and temporal release

UR - http://www.scopus.com/inward/record.url?scp=84908265465&partnerID=8YFLogxK

U2 - 10.2217/nnm.14.126

DO - 10.2217/nnm.14.126

M3 - Review article

C2 - 25343351

AN - SCOPUS:84908265465

SN - 1743-5889

VL - 9

SP - 2023

EP - 2039

JO - Nanomedicine

JF - Nanomedicine

IS - 13

ER -

Gold nanoparticles for photothermally controlled drug release

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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