Gold nanoparticles for photothermally controlled drug release

Ariel R. Guerrero, Natalia Hassan, Carlos A. Escobar, Fernando Albericio, Marcelo J. Kogan, Eyleen Araya

Research output: Contribution to journalReview articlepeer-review

45 Citations (Scopus)

Abstract

In this article, we describe how nanoparticles work in photothermally triggered drug delivery, starting with a description of the plasmon resonance and the photothermal effect, and how this is used to release a drug. Then, we describe the four major functionalization strategies and each of their different applications. Finally, we discuss the biodistribution and toxicity of these systems and the necessary requirements for the use of gold nanoparticles for spatially and temporally controlling drug release through the photothermal effect.

Original languageEnglish
Pages (from-to)2023-2039
Number of pages17
JournalNanomedicine
Volume9
Issue number13
DOIs
Publication statusPublished - 1 Sept 2014

Keywords

  • cancer
  • drug delivery
  • near-infrared irradiation
  • photothermal release
  • spatial and temporal release

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomedical Engineering
  • General Materials Science

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