Genomics of Salmonella contaminating backyard production systems reveals persistence and transmission of genetically related Salmonella on a farm basis

Magaly Toro, Dácil Rivera, Viviana Toledo, Reinaldo Campos-Vargas, Marc W. Allard, Christopher Hamilton-West, Andrea I. Moreno-Switt

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Animals raised in backyard productive systems (BPS) have been frequently associated with Salmonella outbreaks. Several serovars have caused these events, showing that different BPSs can be contaminated by distinct Salmonella serovars. The aim of this study was to characterize the genomic diversity of Salmonella isolates obtained from BPSs in Central Chile to understand their genomic relatedness. A whole-genome SNP-based phylogenetic analysis of 22 Salmonella isolates from 12 locations revealed that S. Typhimurium isolates clustered based on the BPS that they were originally isolated from, and the same was established for S. Enteritidis isolates. Furthermore, our genomic analysis shows that animals from different species (i.e., a chicken, a duck and a pig) carried genetically related S. Typhimurium strains within the same BPS. Moreover, some of these genetically related isolates were obtained in different years (2013 and 2014), indicating that farm-specific Salmonella can persist in BPSs for multiple years and that interspecies transmission is plausible in this environment. Understanding the dynamics of interspecies transmission of Salmonella serovars within a contaminated BPS is fundamental to the design of mitigation strategies to reduce outbreaks of human Salmonella associated with backyard production systems.

Original languageEnglish
Pages (from-to)1008-1014
Number of pages7
JournalZoonoses and Public Health
Volume65
Issue number8
DOIs
Publication statusPublished - 1 Dec 2018

Keywords

  • Chile
  • Salmonella genomics
  • Salmonella in backyard poultry
  • Salmonella transmission in backyard production

ASJC Scopus subject areas

  • Epidemiology
  • Immunology and Microbiology(all)
  • veterinary(all)
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases
  • Immunology
  • Microbiology

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