Genomic lessons from biomining organisms: Case study of the Acidithiobacillus genus

J. H. Valdes, D. S. Holmes

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

4 Citations (Scopus)

Abstract

Advances in DNA sequencing technologies have promoted the use of genome information as a key component in most of biological studies. In the case of biomining microorganisms, partial and complete genome information has provided critical clues for unraveling their physiology. This information has also provided genetic material for the generation of functional and biodiversity directed markers. In this work, we present a compilation of the most relevant findings based on genomic analysis of the model organism Acidithiobacillus ferrooxidans ATCC23270 that were extended and compared to the recently sequenced genomes of Acithiobacillus thiooxidans and Acidithiobacillus caldus. The phylogenetic relatedness of these three microorganisms has permitted the identification of a shared genomic core that encodes the common metabolic and regulatory functions critical for survival and proliferation in extremely acidic environments. We also identified microorganism-specific genomic components that are predicted to be responsible for the metabolic speciation of these microorganisms. Finally, we evaluated the impact of lateral gene transfer on these genomes in order to determine the functional contribution of this phenomenon to the fitness of these microbial representatives. The information gathered by genomic analyses in the Acidithiobacillus genus will be presented in conjunction with other biomining genomic and metagenomic information in order to generate a more comprehensive picture of the biodiversity, metabolism and ecophysiology of the bioleaching niche.

Original languageEnglish
Title of host publicationBiohydrometallurgy 2009
Subtitle of host publicationA Meeting Point between Microbial Ecology, Metal Recovery Processes and Environmental Remediation - Selected, peer rev. papers 18th Int. Biohydrometallurgy Symp., IBS 2009
Pages215-218
Number of pages4
DOIs
Publication statusPublished - 2009
Event18th International Biohydrometallurgy Symposium, IBS 2009 - Bariloche, Argentina
Duration: 13 Sep 200917 Sep 2009

Publication series

NameAdvanced Materials Research
Volume71-73
ISSN (Print)1022-6680

Other

Other18th International Biohydrometallurgy Symposium, IBS 2009
Country/TerritoryArgentina
CityBariloche
Period13/09/0917/09/09

Keywords

  • Acidithiobacillus
  • Bioinformatics
  • Comparative genomics
  • Genome evolution
  • Pangenome

ASJC Scopus subject areas

  • Engineering(all)

Fingerprint

Dive into the research topics of 'Genomic lessons from biomining organisms: Case study of the Acidithiobacillus genus'. Together they form a unique fingerprint.

Cite this