Gene structure of the carp fish ribosomal protein L41: Seasonally regulated expression

Alfredo Molina, Aintzane Corta, Rody San Martin, Marco Alvarez, Luis O. Burzio, Manuel Krauskopf, María Inés Vera

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


The seasonal acclimatization of the carp fish demands physiological compensatory responses. The process involves profound nucleolar adjustments and remarkable changes in rRNA synthesis, which affect ribosomal biogenesis. We have documented that protein kinase CK2, whose activity is related to ribosomal protein L41 and the regulation of rRNA synthesis, was expressed in notably higher amounts in summer-acclimatized carp compared to the cold-season adapted fish. Thus, we approached the study of the functional genomics of carp L41 protein. We report the first cloning of a fish L41 gene encoding the highly conserved 25 amino acids, including approximately 1700 bp regulatory upstream region and the 3′ polyadenylation signal, plus the isolation and characterization of two different L41 cDNAs. We found a clear differential expression of L41, which follows the same pattern as protein kinase CK2β that transcribes at higher levels in the summer-acclimatized carp than it does in the winter-adapted fish.

Original languageEnglish
Pages (from-to)582-586
Number of pages5
JournalBiochemical and Biophysical Research Communications
Issue number3
Publication statusPublished - 2002


  • Acclimatization
  • CK2β subunit
  • Carp
  • Fish
  • L41
  • Ribosomal protein

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology


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