Gastrointestinal microbiome, what is behind faecal microbiota transplantation?

P. Thomson, P. Núñez, R. Quera, C. Bay

Research output: Contribution to journalReview articlepeer-review


The intestinal microbiota is made up of billions of microorganisms that coexist in an organised ecosystem, where strict and facultative anaerobic bacteria predominate. The alteration or imbalance of these microorganisms, known as dysbiosis, can be associated with both gastrointestinal and extraintestinal diseases. Based on a review of the literature, the intestinal microbiota is described in its state of health, the changes associated with some gastrointestinal diseases and the potential role that faecal microbiota transplantation has in the reestablishment of an altered ecosystem. Undoubtedly, the information revealed makes us reflect on the indication of faecal microbiota transplantation in various pathologies of intestinal origin. However, to ensure the efficacy and safety of this therapy, more studies are needed to obtain more evidence.

Original languageEnglish
Article number100898
JournalNew Microbes and New Infections
Publication statusPublished - Jul 2021


  • Dysbiosis
  • faecal microbiota transplantation
  • gastrointestinal illness
  • microbiome

ASJC Scopus subject areas

  • Microbiology
  • Infectious Diseases


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