Endotoxemia-induced endothelial fibrosis inhibition improves hypotension, tachycardia, multiple organ dysfunction syndrome, cytokine response, oxidative stress, and survival

Alejandro Vallejos; Pedro Olivares; Sebastian Gatica; Vicente Villegas; Cesar Echeverria; Claudio Cabello-Verrugio; Felipe Simon

doi:10.1038/s41374-019-0237-6

Endotoxemia-induced endothelial fibrosis inhibition improves hypotension, tachycardia, multiple organ dysfunction syndrome, cytokine response, oxidative stress, and survival

Alejandro Vallejos, Pedro Olivares, Sebastian Gatica, Vicente Villegas, Cesar Echeverria, Claudio Cabello-Verrugio, Felipe Simon

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Original language	English
Pages (from-to)	1173-1192
Number of pages	20
Journal	Laboratory Investigation
Volume	99
Issue number	8
DOIs	https://doi.org/10.1038/s41374-019-0237-6
Publication status	Published - 1 Jul 2019

ASJC Scopus subject areas

Pathology and Forensic Medicine
Molecular Biology
Cell Biology

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10.1038/s41374-019-0237-6

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Vallejos, A., Olivares, P., Gatica, S., Villegas, V., Echeverria, C., Cabello-Verrugio, C., & Simon, F. (2019). Endotoxemia-induced endothelial fibrosis inhibition improves hypotension, tachycardia, multiple organ dysfunction syndrome, cytokine response, oxidative stress, and survival. Laboratory Investigation, 99(8), 1173-1192. https://doi.org/10.1038/s41374-019-0237-6

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title = "Endotoxemia-induced endothelial fibrosis inhibition improves hypotension, tachycardia, multiple organ dysfunction syndrome, cytokine response, oxidative stress, and survival",

author = "Alejandro Vallejos and Pedro Olivares and Sebastian Gatica and Vicente Villegas and Cesar Echeverria and Claudio Cabello-Verrugio and Felipe Simon",

note = "Funding Information: Acknowledgements This work was supported by research grants from Fondo Nacional de Desarrollo Cient{\'i}fico y Tecnol{\'o}gico—FONDE-CYT 1161288 (FS), 11170840 (CE), and 1161646 (CC-V), Millennium Institute on Immunology and Immunotherapy P09-016-F (FS, CC-V), UNAB DI-741-15/N (FS, CC-V).",

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Vallejos, A, Olivares, P, Gatica, S, Villegas, V, Echeverria, C, Cabello-Verrugio, C & Simon, F 2019, 'Endotoxemia-induced endothelial fibrosis inhibition improves hypotension, tachycardia, multiple organ dysfunction syndrome, cytokine response, oxidative stress, and survival', Laboratory Investigation, vol. 99, no. 8, pp. 1173-1192. https://doi.org/10.1038/s41374-019-0237-6

Endotoxemia-induced endothelial fibrosis inhibition improves hypotension, tachycardia, multiple organ dysfunction syndrome, cytokine response, oxidative stress, and survival. / Vallejos, Alejandro; Olivares, Pedro; Gatica, Sebastian et al.
In: Laboratory Investigation, Vol. 99, No. 8, 01.07.2019, p. 1173-1192.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Endotoxemia-induced endothelial fibrosis inhibition improves hypotension, tachycardia, multiple organ dysfunction syndrome, cytokine response, oxidative stress, and survival

AU - Vallejos, Alejandro

AU - Olivares, Pedro

AU - Gatica, Sebastian

AU - Villegas, Vicente

AU - Echeverria, Cesar

AU - Cabello-Verrugio, Claudio

AU - Simon, Felipe

N1 - Funding Information: Acknowledgements This work was supported by research grants from Fondo Nacional de Desarrollo Científico y Tecnológico—FONDE-CYT 1161288 (FS), 11170840 (CE), and 1161646 (CC-V), Millennium Institute on Immunology and Immunotherapy P09-016-F (FS, CC-V), UNAB DI-741-15/N (FS, CC-V).

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JO - Laboratory Investigation

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Endotoxemia-induced endothelial fibrosis inhibition improves hypotension, tachycardia, multiple organ dysfunction syndrome, cytokine response, oxidative stress, and survival

ASJC Scopus subject areas

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