Effectiveness of black tea versus placebo in subjects with hypercholesterolemia: A PRISMA systematic review and meta-analysis

Felipe Araya - Quintanilla, Héctor Gutiérrez - Espinoza, Valeria Moyano – Gálvez, María Jesús Muñoz – Yánez, Leonardo Pavez, Katherine García

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)


Aim: To determine if the black tea is more effective in serum lipid profile that placebo in subjects with hypercholesterolemia. Design: Systematic review with meta-analysis of randomized clinical trials (RCTs). Data sources: The databases Medline, Central, Embase, Lilacs, Cinahl, SPORTDiscus, and Web of Science were searched from inception up to January 2019. Eligibility criteria for selecting studies: RCTs that compared black tea versus placebo, that included serum lipid profile outcomes in subjects older than 18 years of age with hypercholesterolemia. Results: Seven RCTs met the eligibility criteria, and for the quantitative synthesis, six studies were included. Mean difference for total cholesterol was 1.67 mg/dl 95% CI = −5.47 to 8.80 (p = 0.65), mean difference 0.28 mg/dl, 95% CI = −3.89 to 4.45 (p = 0.90) for triglycerides, mean difference 3.21 mg/dl, 95% CI = −11.02 to 4.60 (p = 0.42) for low density lipoprotein-cholesterol, mean difference 0.38 mg/dl, 95% CI = −1.12 to 1.87 (p = 0.62) for high density lipoprotein-cholesterol. Conclusion: In the short term, no significant differences were found in lipid serum profile comparing black tea consumption with placebo.

Original languageEnglish
Pages (from-to)2250-2258
Number of pages9
JournalDiabetes and Metabolic Syndrome: Clinical Research and Reviews
Issue number3
Publication statusPublished - 1 May 2019
Externally publishedYes


  • Black tea
  • Hypercholesterolemia
  • Meta-analysis
  • Serum lipids
  • Systematic review

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism


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