Effectiveness of 6% hydrogen peroxide concentration for tooth bleaching - A double-blind, randomized clinical trial

J. Martín, P. Vildósola, C. Bersezio, A. Herrera, J. Bortolatto, J. R.C. Saad, O. B. Oliveira, E. Fernández

Research output: Contribution to journalArticlepeer-review

72 Citations (Scopus)

Abstract

Objective The aim of this clinical randomized double-blind split-mouth study was to assess the effectiveness of a 6% hydrogen peroxide with nitrogen-doped titanium dioxide light activated bleaching agent. Method 31 patients were treated with: one upper hemiarcade with a 35% hydrogen peroxide bleaching agent and the other hemiarcade with a 6% hydrogen peroxide. Two applications were completed each treatment session and three sessions were appointed, with one week interval between them. Tooth colour was registered each session and 1 week and 1 months after completing the treatment by spectrophotometer, registering parameters L∗, a∗and b∗, and subjectively using VITA Classic guide. Tooth sensitivity was registered by VAS and patient satisfaction and self-perception result was determined using OHIP-14. Tooth colour variation and sensitivity were compared between both bleaching agents. Results Both treatment showed a change between baseline colour and all check-points with a ΔE = 5.57 for 6% and of ΔE = 7.98 for the 35% one month after completing the (p < 0.05). No statistical differences were seen when subjective evaluations were compared. Also, no differences were seen in tooth sensitivity between bleaching agents. OHIP-14 questionnaire demonstrated a significant change for all patients after bleaching. Conclusions A 6% hydrogen peroxide with nitrogen-doped titanium dioxide light activated agent is effective for tooth bleaching, reaching a ΔE of 5.57 one month after completing the treatment, with no clinical differences to a 35% agent neither in colour change or in tooth sensitivity. Clinical significance A low concentration hydrogen peroxide bleaching agent may reach good clinical results with less adverse effects.

Original languageEnglish
Pages (from-to)965-972
Number of pages8
JournalJournal of Dentistry
Volume43
Issue number8
DOIs
Publication statusPublished - 1 Aug 2015

Keywords

  • Bleaching teeth
  • Clinical randomized trial
  • Effectiveness
  • Low concentration
  • OHIP-14
  • Titanium dioxide

ASJC Scopus subject areas

  • General Dentistry

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