The hypoglycemic properties of oat β-glucan is of interest for the food industry and clinical area, for potencial health benefits by reducing glycemic response, serum low-density lipoprotein cholesterol, and glycemic index of meals. There are specific nutritional supplements for diabetics sweetened with sucralose whose glycemic index and glycemic load has not been established. Effect of oat β-glucan on glycemic index and glycemic load of a nutritional supplement sweetened with sucralose in healthy adults was determined in 13 healthy subjects (6 men and 7 women) old that consumed randomly 4 meals of 50 g of carbohydrates each in different days: a nutritional supplement for diabetics (FN), the nutritional supplement with β-glucan incorporated (FN-β) and two reference food, glucose solution (SG) and white bread (PB). Fasting and postprandial glycemia was measured at times 15, 30, 45, 60, 90 and 120 min. The area under the glycemia curve was lower for both formulas (FN) 12697±993, (FN-β) 11584 ±1171 than for reference products (SG) 13900±1245, y (PB) 13267 ± 1557. The values of glycemic index (GI) (FN) 67, 02 ± 5,69 and glycemic load were intermediate and more lower for the supplement with β-glucan incorporated (FN -β) 59, 8 ± 6,2, with no difference of insulin concentration. Suggesting that the addition of oat-derived β-glucan reduces the rate of intestinal absorption of glucose. This effect should be studied in diabetic.
|Translated title of the contribution||Effect of oat β-glucan on glycemic index and glycemic load of a nutritional supplement sweetened with sucralose in healthy adults: A randomized clinical trial|
|Number of pages||9|
|Journal||Archivos Venezolanos de Farmacologia y Terapeutica|
|Publication status||Published - 2016|
ASJC Scopus subject areas
- Pharmacology (medical)