Efectividad de la suplementación de ácidos grasos omega-3 en pacientes con enfermedad de Alzheimer: revisión sistemática con metaanálisis

Translated title of the contribution: Effectiveness of omega-3 fatty acid supplementation in patients with Alzheimer disease: A systematic review and meta-analysis

F. Araya-Quintanilla, H. Gutiérrez-Espinoza, U. Sánchez-Montoya, M. J. Muñoz-Yañez, A. Baeza-Vergara, M. Petersen-Yanjarí, L. Fernández-Lecaros

Research output: Contribution to journalShort surveypeer-review

3 Citations (Scopus)

Abstract

Introduction: Alzheimer disease (AD) is a neurodegenerative disease characterised by progressive dementia associated with global cognitive dysfunction. Methods: We conducted a systematic review and meta-analysis of clinical trials evaluating omega-3 supplementation in patients with AD. Objective: To determine if there is scientific evidence of the effectiveness of omega-3 supplementation in improving cognitive function in patients with AD. Search strategy: We included only randomised controlled trials (RCTs) from the following databases: Medline, Cochrane Central, Cinahl, and LILACS. An electronic search was also conducted using Google Scholar. Study selection: Six articles met the eligibility criteria. The risk of bias was assessed following the Cochrane method. Conclusion: There is no consistent evidence to support the effectiveness of omega-3 supplementation in improving cognitive function in AD patients in the short and medium term.

Translated title of the contributionEffectiveness of omega-3 fatty acid supplementation in patients with Alzheimer disease: A systematic review and meta-analysis
Original languageSpanish
Pages (from-to)105-114
Number of pages10
JournalNeurologia
Volume35
Issue number2
DOIs
Publication statusPublished - Mar 2020
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology

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