Deterioro Cognitivo y Demencias en Adultos con Trastorno del Espectro Autista

Translated title of the contribution: Cognitive impairment and dementia in adults with autism spectrum disorder

David Toloza Ramírez, Carolina Iturra Pedreros, Grisol Iturra Pedreros

Research output: Contribution to journalArticlepeer-review


Autism Spectrum Disorder (ASD) has been studied mainly in children. However, currently, 1/68 adults live with this neurodevelopmental disorder. ASD in adulthood shows suggestive symptoms of cognitive impairment, quickly compromising various cognitive functions. Cognitive impairment and behavioral disorders help to develop neurodegenerative diseases such as Frontotemporal dementia (FTD) and Alzheimer's Disease (AD) in people with ASD during adulthood, which affects activities of daily living (ADL). The objective of this systematic review is to investigate the progression of ASD to cognitive impairment and dementia in adulthood. The methodology included the qualitative analysis of studies published in the years 2000 and 2020, exclusively in english. Results reveal that adults with ASD develop early cognitive impairment and dementia according to the general population, mainly affecting cognitive functions such as memory and executive functions. In conclusion, moderate to a profound degree of intellectual disability, as well as reductions in white matter , seems to be precursors for the development of cognitive impairment and dementia in adults with ASD.

Translated title of the contributionCognitive impairment and dementia in adults with autism spectrum disorder
Original languageSpanish
Pages (from-to)92-102
Number of pages11
JournalRevista Ecuatoriana de Neurologia
Issue number2
Publication statusPublished - 2020

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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