Coqueluche grave: Estado del arte

Translated title of the contribution: Severe pertussis: State of the art

Alejandro Donoso, Daniela Arriagada, Pablo Cruces, Franco Díaz

Research output: Contribution to journalReview articlepeer-review

17 Citations (Scopus)


Pertussis is a contagious disease that has reappeard in the recent years as a public health problem in our country. The clinical presentation has changed especially in the main risk group, children under one year old, evolving in occasions to a highly lethal course called malignant or severe Pertussis. The present review discusses the epidemiology and the mechanisms of pathogenicity, and also describes the risk factors, clinical features and pathophysiology of this particular form. The current evidence and effectiveness of new treatments are described, and a treatment algorithm is proposed.

Translated title of the contributionSevere pertussis: State of the art
Original languageSpanish
Pages (from-to)290-306
Number of pages17
JournalRevista Chilena de Infectologia
Issue number3
Publication statusPublished - Jun 2012

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases


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