Concurrent training and interindividual response in women with a high number of metabolic syndrome risk factors

Pedro Delgado-Floody; Luis Chirosa-Ríos; Felipe Caamaño-Navarrete; Pablo Valdés-Badilla; Tomás Herrera-Valenzuela; Matías Monsalves-Álvarez; Cristian Núñez-Espinosa; Mauricio Castro-Sepulveda; Eduardo Guzmán-Muñoz; David C. Andrade; Cristian Álvarez

doi:10.3389/fphys.2022.934038

Concurrent training and interindividual response in women with a high number of metabolic syndrome risk factors

Pedro Delgado-Floody, Luis Chirosa-Ríos, Felipe Caamaño-Navarrete, Pablo Valdés-Badilla, Tomás Herrera-Valenzuela, Matías Monsalves-Álvarez, Cristian Núñez-Espinosa, Mauricio Castro-Sepulveda, Eduardo Guzmán-Muñoz, David C. Andrade, Cristian Álvarez

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

The non-responders (NRs) after exercise training have been poorly studied in populations with morbid obesity. The purpose of this study was to determine the NR prevalence after 20 weeks of concurrent training of morbidly obese women with a high or low number of metabolic syndrome (MetS) risk factors. Twenty-eight women with morbid obesity participated in an exercise training intervention and were allocated into two groups distributed based on a high (≥3, n = 11) or low number (<3, n = 17) of MetS risk factors. The main outcomes were waist circumference (WC), fasting plasma glucose (FPG), high-density lipids (HDL-c), triglycerides (Tg), and systolic (SBP) and diastolic (DBP) blood pressure, and secondary outcomes were body composition, anthropometric and physical fitness, determined before and after 20 weeks of concurrent training. NRs were defined as previously used technical error cut-off points for the MetS outcomes. Significantly different (all p < 0.05) prevalences of NRs between the H-MetS vs. L-MetS groups (respectively) in WC (NRs 18.2 % vs. 41.1 %, p < 0.0001), SBP (NRs 72.7 % vs. 47.0 %, p = 0.022), DBP (NRs 54.5 % vs. 76.4 %, p < 0.0001), FPG (NRs 100% vs. 64.8 %, p < 0.0001), and HDL-c (NRs 90.9 % vs. 64.7 %, p = 0.012) were observed. In addition, the H-MetS group evidenced significant changes on ΔSBP (−10.2 ± 11.4 mmHg), ΔFPG (−5.8 ± 8.2 mg/dl), ΔHDL-c (+4.0 ± 5.9 mg/dl), and ΔTg (−8.8 ± 33.8 mg/dl), all p < 0.05. The L-MetS group only showed significant changes in ΔWC (−3.8 ± 5.0 cm, p = 0.009). Comparing H-MetS vs. L-MetS groups, significant differences were observed in ∆FPG (−5.8 ± 8.2 vs. +0.3 ± 3.2 mg/dl, p = 0.027), but not in other MetS outcomes. In conclusion, 20 weeks of concurrent training promotes greater beneficial effects in morbidly obese patients with a high number of MetS risk factors. However, the NR prevalence for improving MetS outcomes was significantly superior in these more-diseased groups in SBP, FPG, and HDL-c, independent of their major training-induced effects.

Original language	English
Article number	934038
Journal	Frontiers in Physiology
Volume	13
DOIs	https://doi.org/10.3389/fphys.2022.934038
Publication status	Published - 23 Sept 2022

Keywords

exercise
morbid obesity
physical activity
quality of life
sleep quality

ASJC Scopus subject areas

Physiology
Physiology (medical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3389/fphys.2022.934038

Cite this

Delgado-Floody, P., Chirosa-Ríos, L., Caamaño-Navarrete, F., Valdés-Badilla, P., Herrera-Valenzuela, T., Monsalves-Álvarez, M., Núñez-Espinosa, C., Castro-Sepulveda, M., Guzmán-Muñoz, E., Andrade, D. C., & Álvarez, C. (2022). Concurrent training and interindividual response in women with a high number of metabolic syndrome risk factors. Frontiers in Physiology, 13, Article 934038. https://doi.org/10.3389/fphys.2022.934038

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title = "Concurrent training and interindividual response in women with a high number of metabolic syndrome risk factors",

abstract = "The non-responders (NRs) after exercise training have been poorly studied in populations with morbid obesity. The purpose of this study was to determine the NR prevalence after 20 weeks of concurrent training of morbidly obese women with a high or low number of metabolic syndrome (MetS) risk factors. Twenty-eight women with morbid obesity participated in an exercise training intervention and were allocated into two groups distributed based on a high (≥3, n = 11) or low number (<3, n = 17) of MetS risk factors. The main outcomes were waist circumference (WC), fasting plasma glucose (FPG), high-density lipids (HDL-c), triglycerides (Tg), and systolic (SBP) and diastolic (DBP) blood pressure, and secondary outcomes were body composition, anthropometric and physical fitness, determined before and after 20 weeks of concurrent training. NRs were defined as previously used technical error cut-off points for the MetS outcomes. Significantly different (all p < 0.05) prevalences of NRs between the H-MetS vs. L-MetS groups (respectively) in WC (NRs 18.2 % vs. 41.1 %, p < 0.0001), SBP (NRs 72.7 % vs. 47.0 %, p = 0.022), DBP (NRs 54.5 % vs. 76.4 %, p < 0.0001), FPG (NRs 100% vs. 64.8 %, p < 0.0001), and HDL-c (NRs 90.9 % vs. 64.7 %, p = 0.012) were observed. In addition, the H-MetS group evidenced significant changes on ΔSBP (−10.2 ± 11.4 mmHg), ΔFPG (−5.8 ± 8.2 mg/dl), ΔHDL-c (+4.0 ± 5.9 mg/dl), and ΔTg (−8.8 ± 33.8 mg/dl), all p < 0.05. The L-MetS group only showed significant changes in ΔWC (−3.8 ± 5.0 cm, p = 0.009). Comparing H-MetS vs. L-MetS groups, significant differences were observed in ∆FPG (−5.8 ± 8.2 vs. +0.3 ± 3.2 mg/dl, p = 0.027), but not in other MetS outcomes. In conclusion, 20 weeks of concurrent training promotes greater beneficial effects in morbidly obese patients with a high number of MetS risk factors. However, the NR prevalence for improving MetS outcomes was significantly superior in these more-diseased groups in SBP, FPG, and HDL-c, independent of their major training-induced effects.",

keywords = "exercise, morbid obesity, physical activity, quality of life, sleep quality",

author = "Pedro Delgado-Floody and Luis Chirosa-R{\'i}os and Felipe Caama{\~n}o-Navarrete and Pablo Vald{\'e}s-Badilla and Tom{\'a}s Herrera-Valenzuela and Mat{\'i}as Monsalves-{\'A}lvarez and Cristian N{\'u}{\~n}ez-Espinosa and Mauricio Castro-Sepulveda and Eduardo Guzm{\'a}n-Mu{\~n}oz and Andrade, {David C.} and Cristian {\'A}lvarez",

note = "Publisher Copyright: Copyright {\textcopyright} 2022 Delgado-Floody, Chirosa-R{\'i}os, Caama{\~n}o-Navarrete, Vald{\'e}s-Badilla, Herrera-Valenzuela, Monsalves-{\'A}lvarez, N{\'u}{\~n}ez-Espinosa, Castro-Sepulveda, Guzm{\'a}n-Mu{\~n}oz, Andrade and {\'A}lvarez.",

year = "2022",

month = sep,

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doi = "10.3389/fphys.2022.934038",

language = "English",

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Delgado-Floody, P, Chirosa-Ríos, L, Caamaño-Navarrete, F, Valdés-Badilla, P, Herrera-Valenzuela, T, Monsalves-Álvarez, M, Núñez-Espinosa, C, Castro-Sepulveda, M, Guzmán-Muñoz, E, Andrade, DC & Álvarez, C 2022, 'Concurrent training and interindividual response in women with a high number of metabolic syndrome risk factors', Frontiers in Physiology, vol. 13, 934038. https://doi.org/10.3389/fphys.2022.934038

TY - JOUR

T1 - Concurrent training and interindividual response in women with a high number of metabolic syndrome risk factors

AU - Delgado-Floody, Pedro

AU - Chirosa-Ríos, Luis

AU - Caamaño-Navarrete, Felipe

AU - Valdés-Badilla, Pablo

AU - Herrera-Valenzuela, Tomás

AU - Monsalves-Álvarez, Matías

AU - Núñez-Espinosa, Cristian

AU - Castro-Sepulveda, Mauricio

AU - Guzmán-Muñoz, Eduardo

AU - Andrade, David C.

AU - Álvarez, Cristian

N1 - Publisher Copyright: Copyright © 2022 Delgado-Floody, Chirosa-Ríos, Caamaño-Navarrete, Valdés-Badilla, Herrera-Valenzuela, Monsalves-Álvarez, Núñez-Espinosa, Castro-Sepulveda, Guzmán-Muñoz, Andrade and Álvarez.

PY - 2022/9/23

Y1 - 2022/9/23

N2 - The non-responders (NRs) after exercise training have been poorly studied in populations with morbid obesity. The purpose of this study was to determine the NR prevalence after 20 weeks of concurrent training of morbidly obese women with a high or low number of metabolic syndrome (MetS) risk factors. Twenty-eight women with morbid obesity participated in an exercise training intervention and were allocated into two groups distributed based on a high (≥3, n = 11) or low number (<3, n = 17) of MetS risk factors. The main outcomes were waist circumference (WC), fasting plasma glucose (FPG), high-density lipids (HDL-c), triglycerides (Tg), and systolic (SBP) and diastolic (DBP) blood pressure, and secondary outcomes were body composition, anthropometric and physical fitness, determined before and after 20 weeks of concurrent training. NRs were defined as previously used technical error cut-off points for the MetS outcomes. Significantly different (all p < 0.05) prevalences of NRs between the H-MetS vs. L-MetS groups (respectively) in WC (NRs 18.2 % vs. 41.1 %, p < 0.0001), SBP (NRs 72.7 % vs. 47.0 %, p = 0.022), DBP (NRs 54.5 % vs. 76.4 %, p < 0.0001), FPG (NRs 100% vs. 64.8 %, p < 0.0001), and HDL-c (NRs 90.9 % vs. 64.7 %, p = 0.012) were observed. In addition, the H-MetS group evidenced significant changes on ΔSBP (−10.2 ± 11.4 mmHg), ΔFPG (−5.8 ± 8.2 mg/dl), ΔHDL-c (+4.0 ± 5.9 mg/dl), and ΔTg (−8.8 ± 33.8 mg/dl), all p < 0.05. The L-MetS group only showed significant changes in ΔWC (−3.8 ± 5.0 cm, p = 0.009). Comparing H-MetS vs. L-MetS groups, significant differences were observed in ∆FPG (−5.8 ± 8.2 vs. +0.3 ± 3.2 mg/dl, p = 0.027), but not in other MetS outcomes. In conclusion, 20 weeks of concurrent training promotes greater beneficial effects in morbidly obese patients with a high number of MetS risk factors. However, the NR prevalence for improving MetS outcomes was significantly superior in these more-diseased groups in SBP, FPG, and HDL-c, independent of their major training-induced effects.

AB - The non-responders (NRs) after exercise training have been poorly studied in populations with morbid obesity. The purpose of this study was to determine the NR prevalence after 20 weeks of concurrent training of morbidly obese women with a high or low number of metabolic syndrome (MetS) risk factors. Twenty-eight women with morbid obesity participated in an exercise training intervention and were allocated into two groups distributed based on a high (≥3, n = 11) or low number (<3, n = 17) of MetS risk factors. The main outcomes were waist circumference (WC), fasting plasma glucose (FPG), high-density lipids (HDL-c), triglycerides (Tg), and systolic (SBP) and diastolic (DBP) blood pressure, and secondary outcomes were body composition, anthropometric and physical fitness, determined before and after 20 weeks of concurrent training. NRs were defined as previously used technical error cut-off points for the MetS outcomes. Significantly different (all p < 0.05) prevalences of NRs between the H-MetS vs. L-MetS groups (respectively) in WC (NRs 18.2 % vs. 41.1 %, p < 0.0001), SBP (NRs 72.7 % vs. 47.0 %, p = 0.022), DBP (NRs 54.5 % vs. 76.4 %, p < 0.0001), FPG (NRs 100% vs. 64.8 %, p < 0.0001), and HDL-c (NRs 90.9 % vs. 64.7 %, p = 0.012) were observed. In addition, the H-MetS group evidenced significant changes on ΔSBP (−10.2 ± 11.4 mmHg), ΔFPG (−5.8 ± 8.2 mg/dl), ΔHDL-c (+4.0 ± 5.9 mg/dl), and ΔTg (−8.8 ± 33.8 mg/dl), all p < 0.05. The L-MetS group only showed significant changes in ΔWC (−3.8 ± 5.0 cm, p = 0.009). Comparing H-MetS vs. L-MetS groups, significant differences were observed in ∆FPG (−5.8 ± 8.2 vs. +0.3 ± 3.2 mg/dl, p = 0.027), but not in other MetS outcomes. In conclusion, 20 weeks of concurrent training promotes greater beneficial effects in morbidly obese patients with a high number of MetS risk factors. However, the NR prevalence for improving MetS outcomes was significantly superior in these more-diseased groups in SBP, FPG, and HDL-c, independent of their major training-induced effects.

KW - exercise

KW - morbid obesity

KW - physical activity

KW - quality of life

KW - sleep quality

UR - http://www.scopus.com/inward/record.url?scp=85139560577&partnerID=8YFLogxK

U2 - 10.3389/fphys.2022.934038

DO - 10.3389/fphys.2022.934038

M3 - Article

AN - SCOPUS:85139560577

SN - 1664-042X

VL - 13

JO - Frontiers in Physiology

JF - Frontiers in Physiology

M1 - 934038

ER -

Concurrent training and interindividual response in women with a high number of metabolic syndrome risk factors

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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