Complex Mitochondrial Dysfunction Induced by TPP+-Gentisic Acid and Mitochondrial Translation Inhibition by Doxycycline Evokes Synergistic Lethality in Breast Cancer Cells

Sebastian Fuentes-Retamal, Cristian Sandoval-Acuna, Liliana Peredo-Silva, Daniela Guzman-Rivera, Mario Pavani, Natalia Torrealba, Jaroslav Truksa, Vicente Castro-Castillo, Mabel Catalan, Ulrike Kemmerling, Felix A. Urra, Jorge Ferreira

Research output: Other contributionpeer-review

26 Citations (Scopus)
Original languageEnglish
Publication statusPublished - Feb 2020


  • inhibition of the electron transport chain
  • inhibition of alpha-ketoglutarate dehydrogenase complex
  • mitochondrially targeted
  • decyl polyhydroxybenzoate triphenylphosphonium derivatives
  • doxycycline
  • mitochondrial ribosome inhibition

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