Comparación de la concentración del factor de crecimiento transformante Beta 1 (TGF-β1) en líquido sinovial de perros con y sin enfermedad degenerativa articular

Christof Fischer Wiethuchter; Valentina Lepe; Álvaro Opazo; Álvaro Luzio; Ignacio Troncoso; Carolina Hernandez

doi:10.15381/rivep.v29i3.14758

Comparación de la concentración del factor de crecimiento transformante Beta 1 (TGF-β1) en líquido sinovial de perros con y sin enfermedad degenerativa articular

Translated title of the contribution: Comparison of the concentration of the transforming growth factor beta 1 (TGF-β1) in synovial fluid of dogs with and without degenerative joint disease

Christof Fischer Wiethuchter, Valentina Lepe, Álvaro Opazo, Álvaro Luzio, Ignacio Troncoso, Carolina Hernandez

Life Sciences School

Research output: Contribution to journal › Article › peer-review

Abstract

Degenerative joint disease (DJD) is a non-inflammatory pathology and characterized to be progressive, structural, and functional. The transforming growth factor Beta 1 (TGF-β1) is a regulatory cytokine participating in the production and deposition of extracellular matrix in various tissues, including joint cartilage. The aim of the present study was to compare the concentrations of transforming growth factor β1 in canine synovial fluid with (n=12) and without DJD (n=11), determined by an ELISA test. The mean concentration of TGB-β1 in dogs without DJD was 16.8 ± 7.1 ng/ml, while in dogs with DJD it was 10.3 ± 3.5 ng/ml (p <0.05).

Translated title of the contribution	Comparison of the concentration of the transforming growth factor beta 1 (TGF-β1) in synovial fluid of dogs with and without degenerative joint disease
Original language	Spanish
Pages (from-to)	729-733
Number of pages	5
Journal	Revista de Investigaciones Veterinarias del Peru
Volume	29
Issue number	3
DOIs	https://doi.org/10.15381/rivep.v29i3.14758
Publication status	Published - 1 Jan 2018

ASJC Scopus subject areas

General Veterinary

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10.15381/rivep.v29i3.14758

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@article{20adc8b73eee484e969d57bccc810ed2,

title = "Comparaci{\'o}n de la concentraci{\'o}n del factor de crecimiento transformante Beta 1 (TGF-β1) en l{\'i}quido sinovial de perros con y sin enfermedad degenerativa articular",

abstract = "Degenerative joint disease (DJD) is a non-inflammatory pathology and characterized to be progressive, structural, and functional. The transforming growth factor Beta 1 (TGF-β1) is a regulatory cytokine participating in the production and deposition of extracellular matrix in various tissues, including joint cartilage. The aim of the present study was to compare the concentrations of transforming growth factor β1 in canine synovial fluid with (n=12) and without DJD (n=11), determined by an ELISA test. The mean concentration of TGB-β1 in dogs without DJD was 16.8 ± 7.1 ng/ml, while in dogs with DJD it was 10.3 ± 3.5 ng/ml (p <0.05).",

keywords = "Canines, Synovial fluid, Transforming growth factor β1",

author = "Wiethuchter, {Christof Fischer} and Valentina Lepe and {\'A}lvaro Opazo and {\'A}lvaro Luzio and Ignacio Troncoso and Carolina Hernandez",

year = "2018",

month = jan,

day = "1",

doi = "10.15381/rivep.v29i3.14758",

language = "Espa{\~n}ol",

volume = "29",

pages = "729--733",

journal = "Revista de Investigaciones Veterinarias del Peru",

issn = "1682-3419",

publisher = "Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos",

number = "3",

}

Wiethuchter, CF, Lepe, V, Opazo, Á, Luzio, Á, Troncoso, I & Hernandez, C 2018, 'Comparación de la concentración del factor de crecimiento transformante Beta 1 (TGF-β1) en líquido sinovial de perros con y sin enfermedad degenerativa articular', Revista de Investigaciones Veterinarias del Peru, vol. 29, no. 3, pp. 729-733. https://doi.org/10.15381/rivep.v29i3.14758

Comparación de la concentración del factor de crecimiento transformante Beta 1 (TGF-β1) en líquido sinovial de perros con y sin enfermedad degenerativa articular. / Wiethuchter, Christof Fischer; Lepe, Valentina; Opazo, Álvaro et al.
In: Revista de Investigaciones Veterinarias del Peru, Vol. 29, No. 3, 01.01.2018, p. 729-733.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Comparación de la concentración del factor de crecimiento transformante Beta 1 (TGF-β1) en líquido sinovial de perros con y sin enfermedad degenerativa articular

AU - Wiethuchter, Christof Fischer

AU - Lepe, Valentina

AU - Opazo, Álvaro

AU - Luzio, Álvaro

AU - Troncoso, Ignacio

AU - Hernandez, Carolina

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Degenerative joint disease (DJD) is a non-inflammatory pathology and characterized to be progressive, structural, and functional. The transforming growth factor Beta 1 (TGF-β1) is a regulatory cytokine participating in the production and deposition of extracellular matrix in various tissues, including joint cartilage. The aim of the present study was to compare the concentrations of transforming growth factor β1 in canine synovial fluid with (n=12) and without DJD (n=11), determined by an ELISA test. The mean concentration of TGB-β1 in dogs without DJD was 16.8 ± 7.1 ng/ml, while in dogs with DJD it was 10.3 ± 3.5 ng/ml (p <0.05).

AB - Degenerative joint disease (DJD) is a non-inflammatory pathology and characterized to be progressive, structural, and functional. The transforming growth factor Beta 1 (TGF-β1) is a regulatory cytokine participating in the production and deposition of extracellular matrix in various tissues, including joint cartilage. The aim of the present study was to compare the concentrations of transforming growth factor β1 in canine synovial fluid with (n=12) and without DJD (n=11), determined by an ELISA test. The mean concentration of TGB-β1 in dogs without DJD was 16.8 ± 7.1 ng/ml, while in dogs with DJD it was 10.3 ± 3.5 ng/ml (p <0.05).

KW - Canines

KW - Synovial fluid

KW - Transforming growth factor β1

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U2 - 10.15381/rivep.v29i3.14758

DO - 10.15381/rivep.v29i3.14758

M3 - Artículo

AN - SCOPUS:85054557421

SN - 1682-3419

VL - 29

SP - 729

EP - 733

JO - Revista de Investigaciones Veterinarias del Peru

JF - Revista de Investigaciones Veterinarias del Peru

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Comparación de la concentración del factor de crecimiento transformante Beta 1 (TGF-β1) en líquido sinovial de perros con y sin enfermedad degenerativa articular

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