Calcium stimulation of polyphenylalanine synthesis in a bovine heart cell-free system

Nelson Ruiz, Manuel Krauskopf

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

A bovine myocardial cell-free system, active in polyphenylalanine synthesis, has been studied. When Ca2+ was present under suboptimal Mg2+ concentrations (2 and 5 mM) a marked stimulation of the poly(U) directed macromolecular synthesis was obtained. Calcium did not stimulate the aminoacylation of bovine heart tRNAPhe The evidence suggests that calcium is required, in conjunction with other cations, for an efficient translation of synthetic polynucleotides.

Original languageEnglish
Pages (from-to)2359-2365
Number of pages7
JournalLife Sciences
Volume27
Issue number24
DOIs
Publication statusPublished - 15 Dec 1980

ASJC Scopus subject areas

  • Pharmacology

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