Atypical presentation of pseudomembranous colitis localized in adenomatous polyps

Cristian Hernández-Rocha, Jonathan Barra-Carrasco, Ana María Guzmán, Daniel Paredes-Sabja, Gabriel Lezcano, Pablo Zoroquiaín, Manuel Álvarez-Lobos

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


The most frequent cause of pseudomembranous colitis is Clostridium difficile (C. difficile) infection. This type of colitis is characterized by an endoscopic pattern of numerous small, yellowish or whitish plaques diffusely distributed, which typically compromises the rectum extending to proximal colon. Occasionally, the pseudomembranes compromise only the transverse or right colon, but their exclusive localization over polyps has not been reported. In this case report we have described a patient with symptoms compatible with C. difficile infection and positive for C. difficile toxigenic culture. Colonoscopy examination showed two small polyps with a whitish surface, and histopathological analysis confirmed them to be pseudomembranes over tubular adenomas. The rest of the colonic mucosa was normal and no other cause was demonstrated. We suggest that this particular distribution might be due to a higher affinity for dysplastic cells such as adenomatous polyps of colon by C. difficile and/or its toxins.

Original languageEnglish
Pages (from-to)316-318
Number of pages3
JournalWorld Journal of Gastroenterology
Issue number2
Publication statusPublished - 2013


  • Adenomatous polyps
  • Antibiotic-associated colitis
  • Clostridium difficile
  • Clostridium difficile infections
  • Pseudomembranous colitis

ASJC Scopus subject areas

  • Gastroenterology


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