Anatomy and pathology of tubal pregnancy

C. J. Pauerstein, H. B. Croxatto, C. A. Eddy, I. Ramzy, M. D. Walters

Research output: Contribution to journalArticlepeer-review

71 Citations (Scopus)


The prevalence of tubal pregnancy has increased markedly during the past decade. The reasons for this are obscure. A systematic gross and histopathologic study of 25 consecutive ectopic pregnancies has been performed using a clearing method not used previously for this purpose. In addition, the presence of the corpus luteum and its location in reference to the tubal pregnancy are documented. Results indicate that trophoblastic spread was predominantly intraluminal in 67% of cases. Intratubal hemorrhage, generally in parallel to trophoblastic spread, often led to marked tubal destruction. Histologic evidence of salpingitis was noted in only seven of 24 specimens (29%). The corpus luteum was contralateral to the ectopic pregnancy in five of 21 cases (23.8%). Clinical correlates and areas of future research are discussed. Results indicate that segmental resection of the tubal pregnancy is appropriate in selected cases.

Original languageEnglish
Pages (from-to)301-308
Number of pages8
JournalObstetrics and Gynecology
Issue number3
Publication statusPublished - 1986

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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