An update on post-translational modifications of hydroxyproline-rich glycoproteins: Toward a model highlighting their contribution to plant cell wall architecture

May Hijazi, Silvia M. Velasquez, Elisabeth Jamet, José M. Estevez, Cécile Albenne

Research output: Contribution to journalReview articlepeer-review

74 Citations (Scopus)

Abstract

Plant cell walls are composite structures mainly composed of polysaccharides, also containing a large set of proteins involved in diverse functions such as growth, environmental sensing, signaling, and defense. Research on cell wall proteins (CWPs) is a challenging field since present knowledge of their role into the structure and function of cell walls is very incomplete. Among CWPs, hydroxyproline (Hyp)-rich O-glycoproteins (HRGPs) were classified into three categories: (i) moderately glycosylated extensins (EXTs) able to form covalent scaffolds; (ii) hyperglycosylated arabinogalactan proteins (AGPs); and (iii) Hyp/proline (Pro)-Rich proteins (H/PRPs) that may be non-, weaklyor highly-glycosylated. In this review, we provide a description of the main features of their post-translational modifications (PTMs), biosynthesis, structure, and function. We propose a new model integrating HRGPs and their partners in cell walls. Altogether, they could form a continuous glyco-network with non-cellulosic polysaccharides via covalent bonds or non-covalent interactions, thus strongly contributing to cell wall architecture.

Original languageEnglish
Article number395
JournalFrontiers in Plant Science
Volume5
Issue numberAUG
DOIs
Publication statusPublished - 14 Aug 2014

Keywords

  • Arabinogalactan protein
  • Extensin
  • Hydroxyproline
  • O-glycosylation
  • Proline-rich protein

ASJC Scopus subject areas

  • Plant Science

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