VERONICA ANDREA JIMENEZ CURIHUAL

2024

Chlorin e6-Conjugated Mesoporous Titania Nanorods as Potential Nanoplatform for Photo-Chemotherapy

Vélez-Peña, E., Jiménez, V. A., Manzo-Merino, J., Alderete, J. B. & Campos, C. H., Jun 2024, In: Nanomaterials. 14, 11, 933.

Research output: Contribution to journal › Article › peer-review

Open Access

Enhancement of octreotide antiproliferative activity by PEGylated PAMAM dendrimers delivery

Díaz, C. F., Cifuentes, D. L., Oyarzún, M., Guzmán, J. L. & Jiménez, V. A., 15 Sept 2024, In: Journal of Applied Polymer Science. 141, 35, e55896.

Research output: Contribution to journal › Article › peer-review

Laccase-mediated polymerization of tannins from a pine bark extract: Toward an eco-friendly valorization of forest wastes

Vera, M., Silva, C., Li, N. N., García, Y., Jiménez, V. A. & Urbano, B. F., 10 Jun 2024, In: Journal of Applied Polymer Science. 141, 22, e55437.

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Molecular dynamics simulations in pre-polymerization mixtures for peptide recognition

Polania, L. C. & Jiménez, V. A., Aug 2024, In: Journal of Molecular Modeling. 30, 8, 266.

Research output: Contribution to journal › Article › peer-review

Rational Design and Evaluation of Photoactive Molecularly Imprinted Nanoparticles for Tetracycline Degradation Under Visible Light

García, Y., Aguilar, J., Polania, L., Duarte, Y., Sellergren, B. & Jiménez, V. A., 2024, (Accepted/In press) In: ACS Omega.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Cell internalization kinetics and surface charge accessibility of surface-modified PAMAM dendrimers

Díaz, C. F., Cifuentes, D. L., Oyarzún, M., Jiménez, V. A. & Guzmán, L., 2023, (Accepted/In press) In: Organic and Biomolecular Chemistry. 21, 38, p. 7782-7790 9 p.

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

2022

Drimane Sesquiterpene Alcohols with Activity against Candida Yeast Obtained by Biotransformation with Cladosporium antarcticum

Cortez, N., Marín, V., Jiménez, V. A., Silva, V., Leyton, O., Cabrera-Pardo, J. R., Schmidt, B., Heydenreich, M., Burgos, V., Duran, P. & Paz, C., Nov 2022, In: International Journal of Molecular Sciences. 23, 21, 12995.

Research output: Contribution to journal › Article › peer-review

Open Access

Drimane Sesquiterpene Aldehydes Control Candida Yeast Isolated from Candidemia in Chilean Patients

Marín, V., Bart, B., Cortez, N., Jiménez, V. A., Silva, V., Leyton, O., Cabrera-Pardo, J. R., Schmidt, B., Heydenreich, M., Burgos, V. & Paz, C., Oct 2022, In: International Journal of Molecular Sciences. 23, 19, 11753.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

Insight into the Role of Active Site Protonation States and Water Molecules in the Catalytic Inhibition of DPP4 by Vildagliptin

Corredor, J. D., Febres-Molina, C., Jaña, G. A. & Jiménez, V. A., 2022, (Accepted/In press) In: Journal of Chemical Information and Modeling.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Molecularly imprinted nanoparticle-based assay (MINA) for microcystin-LR detection in water

García, Y., Vera, M., Jiménez, V. A., Barraza, L. F., Aguilar, J., Sánchez, S. & Pereira, E. D., 2022, (Accepted/In press) In: Analyst.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Rational Discovery of Microtubule-Stabilizing Peptides

Úsuga-Acevedo, B., García, Y., Díaz, C. F. & Jiménez, V. A., 2022, (Accepted/In press) In: Journal of Chemical Information and Modeling.

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

2021

Efficient and recyclable gold nanoparticles as catalysts for the cleaner production of 4-morpholinoanilines used as pharmaceutical building blocks

Campos, C. H., Bustamante, T. M., Jiménez, V. A., Torres, C. C. & Alderete, J. B., 25 Mar 2021, In: Journal of Cleaner Production. 290, 125761.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

NanoMIPs Design for Fucose and Mannose Recognition: A Molecular Dynamics Approach

García, Y., Úsuga, B. A., Campos, C. H., Alderete, J. B. & Jiménez, V. A., 26 Apr 2021, In: Journal of Chemical Information and Modeling. 61, 4, p. 2048-2061 14 p.

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

On the Microtubule-Stabilizing Properties of a Tau Oligopeptide

Jiménez, V. A., 22 Nov 2021, In: Journal of Chemical Information and Modeling. 61, 11, p. 5682-5691 10 p.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Polyamidoamine dendrimers of the third generation–chlorin e6 nanoconjugates: Nontoxic hybrid polymers with photodynamic activity

Díaz, C. F., Guzmán, L., Jiménez, V. A. & Alderete, J. B., 2021, (Accepted/In press) In: Journal of Applied Polymer Science.

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Rational Design of Novel Glycomimetic Peptides for E-Selectin Targeting

Jimenez, V. A., Navarrete, K. R., Duque-Norena, M., Marrugo, K. P., Contreras, M. A., Campos, C. H. & Alderete, J. B., 2021, (Accepted/In press) In: Journal of Chemical Information and Modeling.

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

2020

Catalytic Role of Gln202 in the Carboligation Reaction Mechanism of Yeast AHAS: A QM/MM Study

Mendoza, F., Medina, F. E., Jiménez, V. A. & Jaña, G. A., 24 Feb 2020, In: Journal of Chemical Information and Modeling. 60, 2, p. 915-922 8 p.

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Copper metallic nanoparticles capped with PEGylated PAMAM-G3 dendrimers for the catalytic reduction of low solubility nitroarenes of pharmaceutical interest

Jiménez, V. A., Marrugo, K., Campos, C. H., Alderete, J. B. & Torres, C. C., 2020, (Accepted/In press) In: Catalysis Today. 372, p. 27-35 9 p.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Host-guest complexation of curcumin and coumarin 6 with PAMAM-OH: Insight from fluorescence spectroscopy and molecular dynamics simulations

García, Y., Jiménez, V. A. & Alderete, J. B., Jun 2020, In: Journal of Luminescence. 222, 117182.

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Interdimeric Curvature in Tubulin-Tubulin Complexes Delineates the Microtubule-Destabilizing Properties of Plocabulin

Navarrete, K. R. & Jiménez, V. A., 24 Aug 2020, In: Journal of Chemical Information and Modeling. 60, 8, p. 4076-4084 9 p.

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Mechanism-Based Rational Discovery and In Vitro Evaluation of Novel Microtubule Stabilizing Agents with Non-Taxol-Competitive Activity

Zúñiga-Bustos, M., Vásquez, P. A., Jaña, G. A., Guzmán, J. L., Alderete, J. B. & Jiménez, V. A., 22 Jun 2020, In: Journal of Chemical Information and Modeling. 60, 6, p. 3204-3213 10 p.

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Oxidation of isodrimeninol with PCC yields drimane derivatives with activity against candida yeast by inhibition of lanosterol 14-alpha demethylase

Marin, V., Iturra, A., Opazo, A., Schmidt, B., Heydenreich, M., Ortiz, L., Jiménez, V. A. & Paz, C., Aug 2020, In: Biomolecules. 10, 8, p. 1-13 13 p., 1101.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Citations (Scopus)

Polyamidoamine-based nanovector for the efficient delivery of methotrexate to U87 glioma cells

Ortiz, N., Vásquez, P. A., Vidal, F., Díaz, C. F., Guzmán, J. L., Jiménez, V. A. & Alderete, J. B., 1 Dec 2020, In: Nanomedicine (London, England). 15, 28, p. 2771-2784 14 p.

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Rational Design and in Vitro Evaluation of Novel Peptides Binding to Neuroligin-1 for Synaptic Targeting

Vásquez, P., Vidal, F., Torres, J., Jiménez, V. A. & Guzmán, L., 24 Feb 2020, In: Journal of Chemical Information and Modeling. 60, 2, p. 995-1004 10 p.

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Stereospecific Inhibition of Ethanol Potentiation on Glycine Receptor by M554 Stereoisomers

Vásquez, P. A., San Martín, L., Argel, Y., Riquelme, C., Torres, J., Vidal, F., Cayuman, F., Castro, P., Fuentealba, J., Moraga-Cid, G., Yevenes, G., Jin, C., Jiménez, V. A. & Guzmán, L., 2020, (Accepted/In press) In: Journal of Chemical Information and Modeling.

Research output: Contribution to journal › Article › peer-review

Visible-light-responsive folate-conjugated titania and alumina nanotubes for photodynamic therapy applications

Jiménez, V. A., Moreno, N., Guzmán, L., Torres, C. C., Campos, C. H. & Alderete, J. B., 1 Jun 2020, In: Journal of Materials Science. 55, 16, p. 6976-6991 16 p.

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

2019

In Silico Design of Novel Mutant Anti-MUC1 Aptamers for Targeted Cancer Therapy

Santini, B. L., Zúñiga-Bustos, M., Vidal-Limon, A., Alderete, J. B., Águila, S. A. & Jiménez, V. A., 1 Nov 2019, (Accepted/In press) In: Journal of Chemical Information and Modeling. 60, 2, p. 786-793 8 p.

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Modulation of glucan-enzyme interactions by domain V in GTF-SI from Streptococcus mutans

Osorio, M. I., Zúñiga, M. A., Mendoza, F., Jaña, G. A. & Jiménez, V. A., 1 Jan 2019, In: Proteins: Structure, Function and Bioinformatics. 87, 1, p. 74-80 7 p.

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Molecular modeling simulation studies reveal new potential inhibitors against HPV E6 protein

Ricci-López, J., Vidal-Limon, A., Zunñiga, M., Jimènez, V. A., Alderete, J. B., Brizuela, C. A. & Aguila, S., 1 Mar 2019, In: PLoS ONE. 14, 3, e0213028.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Citations (Scopus)

Molecular modeling study on the differential microtubule-stabilizing effect in singly- and doubly-bonded complexes with peloruside A and paclitaxel

Zúñiga, M. A., Alderete, J. B., Jaña, G. A., Navarrete, K. R. & Jiménez, V. A., 1 Jan 2019, In: Proteins: Structure, Function and Bioinformatics. 87, 8, p. 668-678 11 p.

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

The role of conserved arginine in the GH70 family: A computational study of the structural features and their implications on the catalytic mechanism of GTF-SI from: Streptoccocus mutans

Sánchez, L., Mendoza, F., Alderete, J. B., Jiménez, V. A. & Jaña, G. A., 7 Jul 2019, In: Organic and Biomolecular Chemistry. 17, 25, p. 6269-6276 8 p.

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

2018

A QM/MM approach on the structural and stereoelectronic factors governing glycosylation by GTF-SI from: Streptococcus mutans

Jaña, G. A., Mendoza, F., Osorio, M. I., Alderete, J. B., Fernandes, P. A., Ramos, M. J. & Jiménez, V. A., 1 Jan 2018, In: Organic and Biomolecular Chemistry. 16, 14, p. 2438-2447 10 p.

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Cytotoxicity and in vivo plasma kinetic behavior of surface-functionalized PAMAM dendrimers

Diaz, C., Benitez, C., Vidal, F., Barraza, L. F., Jiménez, V. A., Guzman, L., Fuentealba, J., Yevenes, G. E. & Alderete, J. B., 1 Oct 2018, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 14, 7, p. 2227-2234 8 p.

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Effect of pH on Eosin Y/PAMAM interactions studied from absorption spectroscopy and molecular dynamics simulations

Barraza, L. F., Zuñiga, M., Alderete, J. B., Arbeloa, E. M. & Jiménez, V. A., 1 Jul 2018, In: Journal of Luminescence. 199, p. 258-265 8 p.

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Gold catalysts supported on TiO₂-nanotubes for the selective hydrogenation of p-substituted nitrobenzenes

Torres, C. C., Jiménez, V. A., Campos, C. H., Alderete, J. B., Dinamarca, R., Bustamente, T. M. & Pawelec, B., 1 Mar 2018, In: Molecular Catalysis. 447, p. 21-27 7 p.

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Modulation of lateral and longitudinal interdimeric interactions in microtubule models by Laulimalide and Peloruside A association: A molecular modeling approach on the mechanism of microtubule stabilizing agents

Zúñiga, M. A., Alderete, J. B., Jaña, G. A., Fernandez, P. A., Ramos, M. J. & Jiménez, V. A., 1 Jan 2018, (Accepted/In press) In: Chemical Biology and Drug Design. 91, 5, p. 1042-1055 14 p.

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Partially PEGylated PAMAM dendrimers as solubility enhancers of Silybin

Diaz, C., Guzmán, J., Jiménez, V. A. & Alderete, J. B., 9 Aug 2018, In: Pharmaceutical Development and Technology. 23, 7, p. 689-696 8 p.

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

2017

Association of methotrexate with native and PEGylated PAMAM-G4 dendrimers: Effect of the PEGylation degree on the drug-loading capacity and preferential binding sites

Barraza, L. F., Jiménez, V. A. & Alderete, J. B., 1 Jan 2017, In: Journal of Physical Chemistry B. 121, 1, p. 4-12 9 p.

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Binding free energy calculations on E-selectin complexes with sLe^x oligosaccharide analogs

Barra, P. A., Ribeiro, A. J. M., Ramos, M. J., Jiménez, V. A., Alderete, J. B. & Fernandes, P. A., 1 Jan 2017, In: Chemical Biology and Drug Design. 89, 1, p. 114-123 10 p.

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Molecular modeling study on the tubulin-binding modes of epothilone derivatives: Insight into the structural basis for epothilones activity

Jiménez, V. A., Alderete, J. B. & Navarrete, K. R., 2017, (Accepted/In press) In: Chemical Biology and Drug Design. 90, 6, p. 1247-1259 13 p.

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Polyamido amine (PAMAM)-grafted magnetic nanotubes as emerging platforms for the delivery and sustained release of silibinin

Chávez, G., Campos, C. H., Jiménez, V. A., Torres, C. C., Díaz, C., Salas, G., Guzmán, L. & Alderete, J. B., 1 Aug 2017, In: Journal of Materials Science. 52, 16, p. 9269-9281 13 p.

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Structural insight into the role of Gln293Met mutation on the Peloruside A/Laulimalide association with αβ-tubulin from molecular dynamics simulations, binding free energy calculations and weak interactions analysis

Zúñiga, M. A., Alderete, J. B., Jaña, G. A. & Jiménez, V. A., 1 Jul 2017, In: Journal of Computer-Aided Molecular Design. 31, 7, p. 643-652 10 p.

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

2016

Discovery of New E-Selectin Inhibitors by Virtual Screening, Fluorescence Binding Assays, and STD NMR Experiments

Barra, P. A., Jiménez, V. A., Gavin, J. A., Daranas, A. H. & Alderete, J. B., 6 May 2016, In: ChemMedChem. 11, 9, p. 1008-1014 7 p.

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Methotrexate Complexation with Native and PEGylated PAMAM-G4: Effect of the PEGylation Degree on the Drug Loading Capacity and Release Kinetics

Barraza, L. F., Jiménez, V. A. & Alderete, J. B., 1 Feb 2016, In: Macromolecular Chemistry and Physics. 217, 4, p. 605-613 9 p.

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

PAMAM-Conjugated Alumina Nanotubes as Novel Noncytotoxic Nanocarriers with Enhanced Drug Loading and Releasing Performances

Campos, C. H., Díaz, C. F., Guzmán, J. L., Alderete, J. B., Torres, C. C. & Jiménez, V. A., 1 Aug 2016, In: Macromolecular Chemistry and Physics. 217, 15, p. 1712-1722 11 p.

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

PAMAM-grafted TiO₂ nanotubes as novel versatile materials for drug delivery applications

Torres, C. C., Campos, C. H., Diáz, C., Jiménez, V. A., Vidal, F., Guzmán, L. & Alderete, J. B., 1 Aug 2016, In: Materials Science and Engineering C. 65, p. 164-171 8 p.

Research output: Contribution to journal › Article › peer-review

42 Citations (Scopus)

Reversal of ethanol-induced intoxication by a novel modulator of Gβγ protein potentiation of the glycine receptor

Martin, L. S., Cerda, F., Jin, C., Jimenez, V., Yevenes, G. E., Hernandez, T., Nova, D., Fuentealba, J., Aguayo, L. G. & Guzman, L., 2 Sept 2016, In: Journal of Biological Chemistry. 291, 36, p. 18791-18798 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access