LORENA PATRICIA VARELA NALLAR

    • 1371 Citations
    • 22 h-Index
    20002019
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    Fingerprint Dive into the research topics where LORENA PATRICIA VARELA NALLAR is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

    • 7 Similar Profiles
    Wnt Signaling Pathway Medicine & Life Sciences
    Neurogenesis Medicine & Life Sciences
    Neurons Medicine & Life Sciences
    Alzheimer Disease Medicine & Life Sciences
    Catenins Medicine & Life Sciences
    Frizzled Receptors Medicine & Life Sciences
    Copper Medicine & Life Sciences
    Neuronal Plasticity Medicine & Life Sciences

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    Research Output 2000 2019

    • 1371 Citations
    • 22 h-Index
    • 32 Article
    • 8 Review article
    • 1 Chapter
    • 1 Comment/debate
    2 Citations (Scopus)

    Local Klotho Enhances Neuronal Progenitor Proliferation in the Adult Hippocampus

    Salech, F., Varela-Nallar, L., Arredondo, S. B., Bustamante, D. B., Andaur, G. A., Cisneros, R., Ponce, D. P., Ayala, P., Inestrosa, N. C., Valdés, J. L., Behrens, M. I. & Couve, A., 18 Jun 2019, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 74, 7, p. 1043-1051 9 p.

    Research output: Contribution to journalArticle

    Neurogenesis
    Hippocampus
    Knockout Mice
    Calcitriol Receptors
    Stem Cells

    PSD95 regulates morphological development of adult-born granule neurons in the mouse hippocampus

    Mardones, M. D., Jorquera, P. V., Herrera-Soto, A., Ampuero, E., Bustos, F. J., van Zundert, B. & Varela-Nallar, L., 1 Jul 2019, In : Journal of Chemical Neuroanatomy. 98, p. 117-123 7 p.

    Research output: Contribution to journalArticle

    Hippocampus
    Neurons
    Small Interfering RNA
    Dendritic Spines
    Neurogenesis
    19 Citations (Scopus)

    Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer's disease mice

    Bustos, F. J., Ampuero, E., Jury, N., Aguilar, R., Falahi, F., Toledo, J., Ahumada, J., Lata, J., Cubillos, P., Henríquez, B., Guerra, M. V., Stehberg, J., Neve, R. L., Inestrosa, N. C., Wyneken, U., Fuenzalida, M., Härtel, S., Sena-Esteves, M., Varela-Nallar, L., Rots, M. G. & 2 others, Montecino, M. & Van Zundert, B., 1 Dec 2017, In : Brain. 140, 12, p. 3252-3268 17 p.

    Research output: Contribution to journalArticle

    Post-Synaptic Density
    Epigenomics
    Cognition
    Alzheimer Disease
    Proteins
    9 Citations (Scopus)

    NMDA receptor subunit composition controls dendritogenesis of hippocampal neurons through CAMKII, CREB-P, and H3K27ac

    Bustos, F. J., Jury, N., Martinez, P., Ampuero, E., Campos, M., Abarzúa, S., Jaramillo, K., Ibing, S., Mardones, M. D., Haensgen, H., Kzhyshkowska, J., Tevy, M. F., Neve, R., Sanhueza, M., Varela-Nallar, L., Montecino, M. & van Zundert, B., 1 Dec 2017, In : Journal of Cellular Physiology. 232, 12, p. 3677-3692 16 p.

    Research output: Contribution to journalArticle

    Calcium-Calmodulin-Dependent Protein Kinase Type 2
    Cyclic AMP Response Element-Binding Protein
    N-Methyl-D-Aspartate Receptors
    Neurons
    Chemical analysis
    15 Citations (Scopus)

    Frizzled-1 receptor regulates adult hippocampal neurogenesis

    Mardones, M. D., Andaur, G. A., Varas-Godoy, M., Henriquez, J. F., Salech, F., Behrens, M. I., Couve, A., Inestrosa, N. C. & Varela-Nallar, L., 15 Mar 2016, In : Molecular Brain. 9, 1, 209.

    Research output: Contribution to journalArticle

    Frizzled Receptors
    Neurogenesis
    Neurons
    Neural Stem Cells
    Dentate Gyrus