• 225 Citations
  • 8 h-Index
20032019
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Research Output 2003 2019

  • 225 Citations
  • 8 h-Index
  • 13 Article
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Article
2019

Anthraquinone Derivative Reduces Tau Oligomer Progression by Inhibiting Cysteine-Cysteine Interaction

Areche, C., Zapata, F., González, M., Díaz, E., Montecinos, R., Hernández, M., Melo, F. & Cornejo, A., 1 Jan 2019, In : ChemistryOpen.

Research output: Contribution to journalArticle

Open Access
Anthraquinones
Oligomers
Cysteine
tau Proteins
Fluorescence
2018
Depsides
Umbilicaria
tau Proteins
Lichens
Molecular modeling
8 Citations (Scopus)

Secondary metabolite profiling of species of the genus usnea by UHPLC-ESI-OT-MS-MS

Salgado, F., Albornoz, L., Cortéz, C., Stashenko, E., Urrea-Vallejo, K., Nagles, E., Galicia-Virviescas, C., Cornejo, A., Ardiles, A., Simirgiotis, M., García-Beltrán, O. & Areche, C., 1 Jan 2018, In : Molecules. 23, 1, 54.

Research output: Contribution to journalArticle

Usnea
lichens
Lichens
metabolites
Metabolites
2017
12 Citations (Scopus)

Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to β sheet in tau protein linked to Alzheimer’s disease

Cornejo, A., Aguilar Sandoval, F., Caballero, L., Machuca, L., Muñoz, P., Caballero, J., Perry, G., Ardiles, A., Areche, C. & Melo, F., 1 Jan 2017, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 32, 1, p. 945-953 9 p.

Research output: Contribution to journalArticle

tau Proteins
Alzheimer Disease
Tauopathies
Diterpenes
Atomic Force Microscopy
12 Citations (Scopus)

The Polyphenol Altenusin Inhibits in Vitro Fibrillization of Tau and Reduces Induced Tau Pathology in Primary Neurons

Chua, S. W., Cornejo, A., Van Eersel, J., Stevens, C. H., Vaca, I., Cueto, M., Kassiou, M., Gladbach, A., Macmillan, A., Lewis, L., Whan, R. & Ittner, L. M., 19 Apr 2017, In : ACS Chemical Neuroscience. 8, 4, p. 743-751 9 p.

Research output: Contribution to journalArticle

Polyphenols
Pathology
Neurons
Neurofibrillary Tangles
Agglomeration
2016
15 Citations (Scopus)

Secondary metabolites in ramalina terebrata detected by UHPLC/ESI/MS/MS and identification of parietin as tau protein inhibitor

Cornejo, A., Salgado, F., Caballero, J., Vargas, R., Simirgiotis, M. & Areche, C., 18 Aug 2016, In : International Journal of Molecular Sciences. 17, 8, 1303.

Research output: Contribution to journalArticle

tau Proteins
metabolites
Metabolites
inhibitors
Mass Spectrometry
2015
7 Citations (Scopus)

Seco-taondiol, an unusual meroterpenoid from the Chilean seaweed Stypopodium flabelliforme and its gastroprotective effect in mouse model

Areche, C., Benites, J., Cornejo, A., Ruiz, L. M., García-Beltrán, O., Simirgiotis, M. J. & Sepúlveda, B., 1 Apr 2015, In : Marine Drugs. 13, 4, p. 1726-1738 13 p.

Research output: Contribution to journalArticle

Seaweed
Ethylmaleimide
Indomethacin
Prostaglandins
Molecular Structure
2012
3 Citations (Scopus)

A novel monoclonal antibody against the c-terminus of β-tubulin recognizes endocytic organelles in trypanosoma cruzi

Cornejo, A., De Oliveira, C. R., Würtele, M., Chung, J., Hilpert, K. & Schenkman, S., 1 Jan 2012, In : Protein and Peptide Letters. 19, 6, p. 636-643 8 p.

Research output: Contribution to journalArticle

Trypanosoma cruzi
Tubulin
Organelles
Monoclonal Antibodies
Microtubules
2011
34 Citations (Scopus)

Fulvic acid inhibits aggregation and promotes disassembly of tau fibrils associated with alzheimer's disease

Cornejo, A., Jiménez, J. M., Caballero, L., Melo, F. & MacCioni, R. B., 2011, In : Journal of Alzheimer's Disease. 27, 1, p. 143-153 11 p.

Research output: Contribution to journalArticle

Alzheimer Disease
tau Proteins
Humic Substances
Amyloid Plaques
Drug Delivery Systems
32 Citations (Scopus)

Mechanisms of tau self-aggregation and neurotoxicity

Farías, G., Cornejo, A., Jiménez, J., Guzmán, L. & Maccioni, R. B., 1 Sep 2011, In : Current Alzheimer Research. 8, 6, p. 608-614 7 p.

Research output: Contribution to journalArticle

Tauopathies
Alzheimer Disease
tau Proteins
Neurofibrillary Tangles
Post Translational Protein Processing
2009
46 Citations (Scopus)

Trypanosome prereplication machinery contains a single functional Orc1/Cdc6 protein, which is typical of archaea

De Melo Godoy, P. D., Nogueira-Junior, L. A., Paes, L. S., Cornejo, A., Martins, R. M., Silber, A. M., Schenkman, S. & Elias, M. C., Oct 2009, In : Eukaryotic Cell. 8, 10, p. 1592-1603 12 p.

Research output: Contribution to journalArticle

Trypanosomiasis
Archaea
Trypanosoma brucei brucei
Replication Origin
Proteins
2008
25 Citations (Scopus)

Calcineurin B of the human protozoan parasite Trypanosoma cruzi is involved in cell invasion

Araya, J. E., Cornejo, A., Orrego, P. R., Cordero, E. M., Cortéz, M., Olivares, H., Neira, I., Sagua, H., Franco da Silveira, J., Yoshida, N. & González, J., 1 Jul 2008, In : Microbes and Infection. 10, 8, p. 892-900 9 p.

Research output: Contribution to journalArticle

Calcineurin
Trypanosoma cruzi
Parasites
HeLa Cells
Cyclosporine
2003
31 Citations (Scopus)

A novel protein phosphatase 2A (PP2A) is involved in the transformation of human protozoan parasite Trypanosoma cruzi

González, J., Cornejo, A., Santos, M. R. M., Cordero, E. M., Gutiérrez, B., Porcile, P., Mortara, R. A., Sagua, H., Da Silveira, J. F. & Araya, J. E., 15 Sep 2003, In : Biochemical Journal. 374, 3, p. 647-656 10 p.

Research output: Contribution to journalArticle

Protein Phosphatase 2
Trypanosoma cruzi
Parasites
Okadaic Acid
Genes